Postdoctoral Research Associate - Quantitative Microscopy and Live-Cell Chromatin Imaging

Location: Memphis, Tennessee, USA

Company

hirify.global provides a postdoctoral research environment focused on pediatric biomedical science, advanced imaging, and developmental neurobiology.

What you will do

• Develop imaging-based biosensor platforms that make chromatin states visible and measurable in living neurons.
• Optimize biosensor performance, microscopy acquisition, and quantitative analysis of epigenetic modifications and nuclear organization.
• Apply live-cell, lattice light-sheet, and super-resolution microscopy to neuronal differentiation systems.
• Build probes, assays, perturbation workflows, and quantitative image-analysis pipelines.
• Collaborate with cell biologists, developmental neurobiologists, biophysicists, optics experts, and data scientists.
• Define an independent research project and contribute to high-impact experiments and first-author publications.

Requirements

• PhD in cell biology, biophysics, gene regulation, neuroscience, or a related discipline.
• Prior experience with live-cell imaging, advanced microscopy, super-resolution microscopy, single-molecule imaging, lattice light-sheet microscopy, or imaging probe development.
• Interest in chromatin organization, nuclear dynamics, epigenetic regulation, or neuronal differentiation.
• Familiarity with quantitative image analysis using Python, MATLAB, R, Fiji/ImageJ, Imaris, or related platforms.
• Strong record of peer-reviewed publications and ability to prepare, validate, document, and troubleshoot experiments.

Nice to have

• Experience with segmentation, tracking, registration, time-series analysis, or automated image-processing workflows.
• Experience with fluorescent probes, biosensors, HaloTag/SNAP-tag systems, protein engineering, or live-cell assay development.

Culture & Benefits

• Access to advanced microscopy platforms and collaborative core laboratories.
• Support from data science experts and an interdisciplinary research environment.
• Opportunities to develop new imaging probes, biosensor systems, and analytical methods.
• Scientific training focused on chromatin-state dynamics, neuronal maturation, and brain circuit assembly.

Hiring process

• Submit a C.V., description of research interests, outline of career aspirations, and contact information for three referees.
• Describe in the cover letter an imaging system, protocol, or project personally built or improved, including the changes made, reliability validation, and resulting discovery.