Senior Director, Oncology Pharmacology

Location: Remote/Home-Based for US-based candidates in California, Palo Alto, CA, or Philadelphia, PA

Salary: $232,000–$348,000 USD base pay, plus potential bonus, equity, and benefits.

Company

hirify.global is a global biopharmaceutical company developing medicines for serious diseases, with a growing portfolio of oncology treatments and research programs.

What you will do

• Lead oncology pharmacology scientists and serve as a pharmacology lead for one or more programs from discovery through regulatory approval.
• Design and execute studies assessing efficacy, tolerability, mechanisms of action, pharmacodynamics, and biomarkers in hematologic malignancies and solid tumors.
• Evaluate therapeutic combinations and modalities including small molecules, biologics, ADCs, bispecifics, cell therapies, gene therapies, and RNA-based therapeutics.
• Manage CRO and academic research collaborations, including protocols, timelines, budgets, study execution, and data interpretation.
• Collaborate with Clinical Development, Bioanalytical, Toxicology, Clinical Pharmacology, Biomarkers, Regulatory Affairs, and Project Management teams.
• Prepare technical reports and contribute to IND, NDA/BLA/MAA, briefing package, DSUR, IB, and fast-track designation documentation.

Requirements

• Ph.D. in biology, biochemistry, immunology, pharmacology, or a related discipline.
• Extensive industry experience in oncology drug development, from hit-to-lead optimization through IND-enabling studies.
• Deep immuno-oncology expertise, including in vivo and in vitro models, immune cell biology, and immunological endpoints.
• Experience across multiple therapeutic modalities and with cancer signaling pathways.
• Proven leadership of complex pharmacology programs across CROs, including GLP and non-GLP studies.
• Direct people management, strong project management, analytical skills, and experience authoring nonclinical regulatory submissions.

Culture & Benefits

• Remote/home-based work arrangement for the specified US locations.
• Highly matrixed, cross-functional collaboration across internal teams, academia, industry, CROs, and regulatory agencies.
• Medical, dental, and vision insurance.
• 401(k) retirement savings plan and flexible paid vacation.
• Potential annual cash bonus or incentive compensation and discretionary equity grants.