Director, Clinical Pharmacology (Oncology)

Location: Hybrid/remote within the United States, with Salt Lake City or New York City as preferred home bases. Remote employees must commit to regular on-site visits for routine work and departmental events.

Annual base salary: $212,900–$297,000, depending on location, skills, experience, and qualifications. The role is also eligible for an annual bonus and equity compensation.

Company

hirify.global is a clinical-stage TechBio company developing medicines through an AI-native platform that integrates biology, chemistry, and clinical development.

What you will do

• Lead clinical pharmacology and pharmacometric strategy and execution across rare disease and oncology clinical programs.
• Develop clinical pharmacology strategies that support product development plans and regulatory interactions.
• Provide pharmacology input into Phase 1–3 clinical studies and dedicated clinical pharmacology studies.
• Author clinical pharmacology sections of Investigator’s Brochures, INDs, NDAs, and other regulatory submissions.
• Collaborate with clinical development, translational, preclinical, DMPK, toxicology, and due diligence teams.
• Oversee or perform modeling and simulation to support dose selection, exposure-response, and exposure-safety decisions.

Requirements

• Ph.D. in Pharmaceutical Sciences, Pharmacokinetics, or a related discipline; M.D. with clinical pharmacology expertise; or Pharm.D. with a clinical pharmacology fellowship.
• 5–9+ years of experience in biotech or pharmaceutical drug development.
• Demonstrated success leading clinical pharmacology aspects of drug development.
• Experience with PK, PK-PD, and PK-safety analyses, including non-compartmental analysis, population PK modeling, and PK-PD modeling and simulations.
• Proficiency with WinNonlin, Monolix, NONMEM, R, or other modeling software.
• Experience preparing regulatory submissions, responding to health authority questions, and participating in regulatory meetings.

Nice to have

• Experience in oncology drug development.

Culture & Benefits

• Work in a cross-functional Development Sciences organization spanning discovery and development projects.
• Collaborate with clinical science, clinical operations, regulatory affairs, biostatistics, DMPK, biology, chemistry, and translational biomarker functions.
• Annual bonus and equity compensation.
• Comprehensive employee benefits package.
• Company values emphasize scientific integrity, ownership, active learning, urgency, and direct collaboration.