Senior Director, Quantitative Pharmacology

Location: Remote; compensation information applies to individuals hired to perform the role in the United States.

Salary: $230,720–$345,000 annually, plus incentive opportunity.

Company

hirify.global Pharmaceutical Companies develops pharmaceutical products and conducts drug development across clinical and translational research programs.

What you will do

• Lead clinical pharmacology activities across pre-IND, IND, Phase 1–3, and registrational development programs for small- and large-molecule drugs.
• Develop and optimize clinical pharmacology strategies, including dose finding, dose optimization, exposure-response analyses, pediatric development, and study design.
• Review, approve, and lead clinical pharmacology reports, PK/PD analyses, regulatory filing sections, and related development documentation.
• Serve as the clinical pharmacology lead on cross-functional teams and communicate data-driven strategies and recommendations to development teams.
• Coordinate with pharmacometrics, biomarker, bioanalytical, toxicology, ADME, clinical, regulatory, statistics, formulation, and CMC functions.
• Review business development opportunities, contribute to QTR strategy, and train and mentor junior quantitative pharmacology team members.

Requirements

• PhD in clinical pharmacology or a related field such as pharmacokinetics, pharmacology, or pharmaceutics.
• At least 12 years of experience in clinical pharmacology or related areas.
• Extensive experience developing and executing clinical pharmacology strategies from early-stage through late-stage and registrational programs.
• In-depth knowledge of early-phase study design, PK, PD, drug metabolism, biopharmaceutics, biomarkers, and bioanalytical assays for small molecules and monoclonal antibodies.
• Hands-on experience with PK and PK/PD data analysis, including Phoenix NLME, and strong knowledge of Phase I clinical operations and multi-region regulatory requirements.
• Strong leadership, communication, organization, scientific problem-solving, and cross-functional collaboration skills.

Nice to have

• Experience developing early-phase clinical protocols.

Culture & Benefits

• Remote work arrangement with approximately 20% travel.
• Medical, dental, vision, and prescription drug coverage.
• Basic life, accidental death and dismemberment, and short- and long-term disability insurance.
• Tuition reimbursement, student loan assistance, and a generous 401(k) match.
• Flexible time off, paid holidays, and paid leave programs.