Global Medical Director, Medical Affairs (Rare Disease Biotech)

Location: Waltham, Massachusetts, United States; onsite

Salary: $215,000–$260,000 USD base pay

Company

hirify.global develops therapeutics targeting muscle and the central nervous system to deliver functional improvement for people living with genetically driven neuromuscular diseases.

What you will do

• Lead Global Medical Affairs strategy for assigned neuromuscular disease programs and represent Medical Affairs on cross-functional program, clinical development, evidence generation, and launch readiness teams.
• Develop and execute integrated global medical plans covering scientific understanding, evidence generation, external engagement, and launch preparation.
• Guide KOL, payer, investigator, healthcare professional, patient advocacy, and other external stakeholder engagement strategies.
• Partner with Clinical Development, Clinical Operations, Regulatory Affairs, Biometrics, Translational Medicine, Value and Access, Commercial, and regional medical teams on trial planning, data interpretation, patient journeys, diagnostic pathways, and Target Product Profile development.
• Identify evidence gaps and support real-world evidence, natural history, registry, investigator-sponsored research, post hoc analysis, publication, congress, medical education, and scientific communications activities.
• Translate external insights and emerging data into recommendations for global medical strategy, lifecycle planning, partnered assets, and cross-functional decisions.

Requirements

• Advanced scientific or clinical degree required; MD, PhD, PharmD, or equivalent doctoral degree preferred.
• 10+ years of relevant experience, including 6+ years in industry Medical Affairs, Clinical Development, Scientific Communications, or related pharmaceutical or biotechnology roles.
• Experience in rare disease required; neuromuscular disease, genetic medicines, oligonucleotide therapeutics, or ASOs strongly preferred.
• Demonstrated ability to develop medical, evidence generation, KOL engagement, congress, publication, and medical education strategies.
• Strong scientific, communication, collaboration, influencing, prioritization, and problem-solving skills, including the ability to drive alignment without direct authority.
• Must be authorized to work in the United States and willing to travel as needed.

Culture & Benefits

• Work in a fast-paced, growing biotechnology company focused on patients and scientific innovation.
• Collaborative, matrixed environment emphasizing integrity, accountability, scientific excellence, and compliance.
• Opportunity to contribute to programs addressing Duchenne muscular dystrophy, myotonic dystrophy type 1, facioscapulohumeral muscular dystrophy, Pompe disease, and multiple DMD mutations.
• Base compensation is determined by education, experience, job-related knowledge, and demonstrated skills.