Associate Scientist (In vivo Pharmacology, Inflammation)

Location: United States; locations listed include Thousand Oaks and South San Francisco, California

Company

Amgen is a biotechnology company developing medicines across oncology, inflammation, general medicine, and rare disease.

What you will do

• Execute in vivo preclinical disease models, primarily using mice and possibly rats, in the vivarium.
• Provide technical support for dosing, sample and tissue collection, health checks, study setup, and takedown.
• Work with Scientists and Senior Scientists to execute and help design experiments.
• Run concurrent studies while maintaining organization, accurate records, and study timelines.
• Support in vitro assays and communicate results to the immediate team.
• Participate in weekend and evening dosing rotations as needed while following protocols and safety procedures.

Requirements

• Master’s degree and 1 year of Immunology or related experience, or Bachelor’s degree and 3 years of Immunology or related experience.
• Strong understanding of Immunology and Inflammation biology and demonstrated experience with pharmacology and in vivo inflammation or immunology models.
• Significant experience designing and executing concurrent in vivo preclinical inflammation and autoimmune disease models.
• Hands-on experience with in vivo dosing, administration routes, bleeds, necropsy, organ collection, cardiac bleed, and lung BAL collection.
• Hands-on experience with multicolor flow cytometry, including spectral flow approaches and immune-cell populations, is essential.
• Experience with cellular, biochemical, histological, and molecular biology assays, along with proficiency in GraphPad Prism, Excel, PowerPoint, and Word.

Nice to have

• Experience with colitis, lupus, arthritis, or GvHD models.
• Experience in asthma, COPD, HS, or PBC research.
• Track record of independent critical thinking, scientific achievement, and productivity.

Culture & Benefits

• Collaborative, innovative, and science-based work environment.
• Health, dental, and vision coverage, life and disability insurance, and flexible spending accounts.
• Retirement and savings plan with company contributions.
• Annual bonus program and stock-based long-term incentives.
• Paid time off, work-life balance support, and career development opportunities.
• Flexible work models where applicable to the role.

Hiring process

• Applications remain open until a sufficient number of applications are received or a candidate is selected.
• Sponsorship for this role is not guaranteed.