8 часов назад
Associate Scientist, In vivo Pharmacology, Inflammation
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Associate Scientist, In vivo Pharmacology, Inflammation (Immunology): Executing in vivo preclinical inflammation and autoimmune disease models and in vitro assays to support drug discovery pipeline programs with an accent on hands-on animal dosing, tissue collection, and immunology research. Focus on designing and running concurrent studies, performing multicolor flow cytometry and molecular assays, and communicating accurate results within study timelines.
Location: Corporate Headquarters, Thousand Oaks, California, United States
Company
develops and delivers biotech medicines across oncology, inflammation, general medicine, and rare disease.
What you will do
- Execute in vivo preclinical disease models, primarily using mice and potentially rats, in the vivarium.
- Provide technical support for dosing, sample and tissue collection, health checks, study setup, and study closeout.
- Work with Scientists and Senior Scientists to execute and help design experiments.
- Run concurrent studies while maintaining accurate records and meeting study timelines.
- Support in vitro assays and communicate results to the immediate team.
- Participate in weekend and evening dosing rotations as needed.
Requirements
- Master’s degree plus 1 year of Immunology or related experience, or Bachelor’s degree plus 3 years of Immunology or related experience.
- Strong understanding of Immunology and Inflammation biology.
- Significant experience designing and executing in vivo preclinical inflammation or autoimmune disease models.
- Hands-on experience with in vivo dosing, bleeds, necropsy, organ collection, cardiac bleeds, and lung BAL collection.
- Essential: hands-on experience with multicolor flow cytometry, including spectral flow approaches and immune cell populations.
- Strong organization, communication, critical-thinking, record-keeping, and data-analysis skills, with proficiency in GraphPad Prism and Microsoft Office.
Nice to have
- Experience with colitis, lupus, arthritis, or GvHD models.
- Experience with asthma, COPD, HS, or PBC models.
- Hands-on experience with cellular, biochemical, histological, and molecular biology assays such as ELISA, MSD, quantitative RT-PCR, and BCA protein measurements.
Culture & Benefits
- Collaborative, innovative, science-based work environment.
- Health, dental, vision, life, disability, and flexible spending benefits for eligible employees and dependents.
- Retirement and savings plan with company contributions.
- Annual bonus program, stock-based long-term incentives, and award-winning time-off plans.
- Career development opportunities and flexible work models where applicable.
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