Scientist I, Microglia

Location: On-site in Torrey Pines, San Diego, California. Flexible availability for weekend and holiday work may be required. Relocation is not available.

Salary: $108,900–$133,100 annually for candidates working in San Diego.

Company

hirify.global develops iPSC-derived cell therapy products and therapeutic programs for patients with significant medical needs.

What you will do

• Design and execute experiments involving microglia differentiation, characterization, translational research, and preclinical studies.
• Lead the development, optimization, and characterization of iPSC-derived microglia processes.
• Conduct in vitro and in vivo studies evaluating cellular phenotype, function, engraftment, therapeutic activity, and disease mechanisms.
• Analyze and interpret experimental data, troubleshoot projects, and contribute to technical reports and other documentation.
• Collaborate with cross-functional departments, scientific leadership, external academic partners, and contract research organizations.
• Support cell therapy product release, stability, characterization, pipeline expansion, and the training of Research Associates.

Requirements

• PhD in biology, neuroscience, or a related discipline, or equivalent education and experience.
• At least 3 years of hands-on experience in a molecular or cellular research environment.
• Proficiency in aseptic cell culture with experience in hESCs or hiPSCs.
• Competence in designing, optimizing, and validating gene-editing experiments.
• Strong data analysis, quantitative, organizational, written, and verbal communication skills.
• Valid U.S. work authorization that does not require employer sponsorship now or in the future is required.

Nice to have

• Experience with iPSCs, microglia, in vivo disease modeling, gene editing, or bioinformatics.
• Experience with preclinical animal studies, tissue collection, histological analysis, and in vivo efficacy evaluation.
• Experience with flow cytometry, qRT-PCR, RNA-seq, IHC, live-cell imaging, calcium imaging, or MEA.
• Background in microglia, macrophages, neuroinflammation, neurodegeneration, or CNS disease models.

Culture & Benefits

• Collaborative, learning-focused environment with opportunities to contribute to product development.
• Medical and dental insurance benefits.
• Paid time off in addition to company-observed holidays.
• On-site gym and other wellness benefits.
• Laboratory safety training and personal protective equipment are provided.