2 дня назад
Sr Scientist, Antibody Discovery
131 000 - 142 600$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Sr Scientist, Antibody Discovery (Antibody Characterization): Supporting therapeutic antibody discovery programs through bioanalytical characterization, assay development, data analysis, and customer reporting with an accent on SPR/BLI affinity analysis, developability assays, and functional screening. Focus on leading concurrent in vivo antibody discovery projects, troubleshooting complex workflows, integrating advanced assays, and balancing scientific analysis with wet-lab execution.
Location: Onsite in Quincy, Massachusetts, USA
Base compensation: $131,000–$142,600 USD annually, plus bonus, equity, and benefits.
Company
develops silicon-based DNA synthesis technologies for applications in healthcare, agriculture, industrial chemicals, and data storage.
What you will do
- Support multiple antibody discovery projects as an individual-contributor Project Lead without direct people management.
- Analyze, optimize, and troubleshoot SPR, BLI, developability, ELISA, flow cytometry, kinetic, and functional assays.
- Provide technical guidance on assay development, data analysis, reporting, feasibility, and assay integration.
- Lead end-to-end technical work for in vivo antibody discovery programs and contract services.
- Review, critically analyze, and present complex scientific data to internal and external customers.
- Coordinate timelines, deliverables, risks, and progress with Project Management and cross-functional teams while spending approximately 80% of time on analysis and 20% on wet-lab work.
Requirements
- PhD in a related technical field with 5+ years of biopharmaceutical analytical development experience, or a master’s degree with 10+ years of experience.
- Expert hands-on knowledge of antibody and biologics characterization, including Carterra SPR, Octet BLI, ELISA, flow cytometry, and developability assays.
- Experience with HPLC, high-throughput plate-based assays, SDS-PAGE, protein quantification, and endotoxin assays.
- Advanced understanding of in vivo antibody discovery, high-throughput screening, epitope binning, ligand blocking, affinity analysis, and cell-based functional assays.
- Ability to manage concurrent, time-critical workflows, troubleshoot processes, make sound scientific decisions, and present complex data accurately.
- Strong written and verbal communication skills, including external customer-facing communication.
Nice to have
- Experience running high-throughput assays involving thousands of samples.
Culture & Benefits
- Cross-functional collaboration across scientific, wet-lab, project management, and leadership teams.
- Equal employment opportunity workplace.
- Eligibility for bonus, equity, and a generous benefits package.
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