Scientist/ Senior Scientist - Translational Cardiac Biology

Location: Bay Area, on-site

Salary: $120,000–$180,000 per year, plus potential equity.

Company

hirify.global is an early-stage moonshot company developing organ-scale reversible cryopreservation technologies, including perfusion systems, cryoprotectant formulations, vitrification, and rewarming hardware.

What you will do

• Develop clinically translatable cardiac in vitro models using primary, immortalized, and iPSC-derived cardiomyocytes.
• Design and execute high-throughput screening experiments to measure cardiac-cell viability and functional performance.
• Create and validate 3D cardiac models, including organoids, engineered heart tissues, and micro-tissues.
• Characterize cardiotoxicity, permeability, contractility, electrophysiology, and calcium handling for new cryoprotectant compounds.
• Apply plate-reader, flow cytometry, and genomics techniques, including GWAS, RNA sequencing, and FISH, to refine models and support molecular discovery.
• Collaborate across disciplines, translate findings into cryoprotectant formulations, and mentor team members.

Requirements

• PhD or postdoctoral training in cardiac physiology, bioengineering, chemical engineering, tissue engineering, pharmacology, toxicology, or a related field, or 4+ years of equivalent industry experience leading research projects.
• Independent experience developing and executing complex experiments in cardiac biology or a related therapeutic area.
• Hands-on expertise in cell-based assay development with primary cells, iPSC-derived cell types, or 3D in vitro models.
• Experience designing high-throughput screening workflows and analyzing multiparametric datasets.
• Ability to collaborate effectively in a fast-paced, mission-driven environment.

Nice to have

• Experience applying pharmacokinetic and pharmacodynamic frameworks to cryoprotectant formulation development.
• Experience with cardiac electrophysiology, contractility measurement, or calcium imaging.
• Peer-reviewed publications in cardiac biology, cryobiology, toxicology, or related fields.

Culture & Benefits

• Opportunity to contribute as an early team member to organ-scale reversible cryopreservation.
• Medical, dental, and vision insurance for employees and dependents.
• Flexible time off and paid holidays.
• Competitive compensation with salary and equity.
• 401(k), FSA, commuter benefits, and subsidized daily lunch.