1 час назад
Senior Research Associate (Molecular Biology)
109 200 - 140 000$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Senior Research Associate (Molecular Biology): Developing discovery platforms for target identification, mechanistic studies, and therapeutic validation across cell engineering, perturbation screens, and translational model systems with an accent on mammalian cell culture, molecular biology, and functional genomics. Focus on designing complex bench workflows, optimizing viral and non-viral delivery systems, executing CRISPR perturbation studies, and building robust cell-based assays for cellular rejuvenation research.
Location: San Francisco Bay Area, California, United States; salary range specified for Redwood City
Salary: $109,200–$140,000 per year for the Senior Research Associate role in Redwood City
Company
is a biotechnology research company focused on restoring cell health and resilience through cell rejuvenation to address disease, injury, and age-related disability.
What you will do
- Maintain, expand, characterize, and troubleshoot immortalized and primary mammalian cell culture systems.
- Design and execute molecular biology workflows, including cloning, plasmid construction, nucleic acid preparation, and mRNA design and synthesis.
- Produce, optimize, and deploy lentiviral, AAV, and LNP delivery systems for gene perturbation, expression, and cellular engineering studies.
- Perform CRISPR genome editing, pooled and arrayed perturbation workflows, and follow-up validation experiments.
- Develop and optimize cell-based assays, reporter systems, and phenotypic readouts for discovery and therapeutic validation.
- Maintain thorough ELN documentation and help establish scalable SOPs and laboratory best practices.
Requirements
- BS or MS in Molecular Biology, Cell Biology, Biochemistry, Bioengineering, or a related discipline.
- At least 2 years of relevant hands-on experience in biotech, pharma, or a leading academic laboratory.
- Strong mammalian cell culture and molecular biology experience, including cloning and nucleic acid-based assays.
- Experience with viral transduction, gene delivery, and/or genome editing platforms.
- Ability to troubleshoot experiments independently, manage multiple priorities, and deliver reproducible, high-quality work.
- Strong organization, communication, scientific rigor, and ownership of complex workflows.
Nice to have
- Experience with primary human cells, stem cells, organoids, ex vivo platforms, or other advanced cellular models.
- Experience with CRISPR screens, Perturb-seq, or high-throughput perturbation platforms.
- Experience with single-cell RNA-seq, single-nucleus RNA-seq, spatial transcriptomics, or related omics workflows.
- Experience with flow cytometry, imaging, high-content screening, or automated cell analysis.
- Interest or experience in aging biology, regenerative medicine, or cellular rejuvenation.
Culture & Benefits
- Collaborative environment focused on scientific excellence and discovery.
- Inclusive culture centered on belonging and diverse perspectives.
- Opportunity to contribute to cell rejuvenation research and next-generation discovery approaches.
- Employment opportunities are provided without unlawful discrimination or harassment.
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