2 дня назад
Senior Scientist, Biologics Formulation (Biopharmaceutical Formulation)
140 000 - 180 000$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Senior Scientist, Biologics Formulation (Biopharmaceutical Formulation): Leading protein formulation development programs for high-concentration biologics and advanced formulation systems with an accent on protein chemistry, physical biochemistry, and colloidal stability. Focus on designing complex experiments, mitigating aggregation and degradation risks, and establishing analytical workflows and quality standards for space-based biomanufacturing.
Location: On-site in El Segundo, California, United States. Candidates must be U.S. persons authorized to work in the United States and permitted to access export-controlled technology.
Salary: $140,000–$180,000 per year, plus potential stock options and/or long-term cash awards.
Company
develops commercial space infrastructure, including in-orbit pharmaceutical processing, reentry capsules, heat shields, and satellite buses.
What you will do
- Lead formulation development programs for high-concentration protein therapeutics across dosage forms.
- Design formulation strategies using protein chemistry, physical biochemistry, thermodynamics, solution chemistry, and colloidal science.
- Identify and mitigate aggregation, precipitation, viscosity, and chemical degradation risks, including defining Critical Quality Attributes.
- Lead multiple formulation projects, design experiments, interpret complex datasets, and establish acceptance criteria.
- Evaluate advanced formulation technologies and collaborate with analytical development, engineering, and external partners.
- Mentor junior scientists and maintain rigorous data management, ELN documentation, technical reporting, and publication practices.
Requirements
- PhD in Pharmaceutical Sciences, Biomaterials, Materials Science, Chemistry, Chemical Engineering, Biochemistry, or a related discipline.
- At least 3 years of biopharmaceutical industry experience in early-stage or late-stage protein formulation development.
- Proven experience leading formulation development projects from concept through execution.
- Deep expertise in protein chemistry, physical biochemistry, formulation science, and high-concentration protein formulations.
- Hands-on experience with protein characterization techniques such as DLS, DSF, SEC, CE, rheology, and spectroscopy.
- U.S. person status and authorization to work in the United States are required for access to export-controlled technology.
Nice to have
- Experience with protein crystallization, lyophilization, spray drying, or other solid-state processing operations.
- Knowledge of advanced formulation systems, Design of Experiments, statistical analysis, high-throughput screening, or automation.
- Background in monoclonal antibodies, antibody-drug conjugates, or other complex biologics.
- Scientific publications, patent applications, or experience in startup and resource-constrained R&D environments.
Culture & Benefits
- Scientific autonomy and the opportunity to shape formulation development for space-based biomanufacturing.
- Collaborative work with scientists and engineers across pharmaceutical processing, spacecraft, and manufacturing programs.
- Flexible PTO, 12 paid holidays, parental leave, and company-paid medical, dental, and vision insurance.
- FSA and employer-matched HSA options, wellness reimbursement, and a 401(k) with a 6% employer match.
- Relocation support for new hires if needed, daily lunch, twice-weekly dinner, team events, and complimentary EV charging.
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