2 дня назад
Biologics Formulation Research Internship (Biologics)
33$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Biologics Formulation Research Internship (Biologics) (protein characterization and formulation): Characterizing biologic drug candidates and evaluating formulation stability for pharmaceutical manufacturing in microgravity with an accent on biophysical analysis, binding studies, and freeze-drying processes. Focus on designing laboratory experiments, interpreting protein structure and stability data, and documenting analytical results.
Location: Full-time, on-site in El Segundo, California, United States. Spring internships run between January and May, depending on the selected student's university schedule.
Hourly rate: $33.00. Housing stipend is available for interns relocating to the area, with a commuter benefit for local transportation.
Company
develops commercial space infrastructure, including in-orbit pharmaceutical processing payloads, reentry capsules, heat shields, and satellite buses.
What you will do
- Perform biophysical characterization of protein candidates to assess structure, stability, purity, charge variants, and interaction behavior.
- Design and execute binding and selection studies involving disordered protein stabilizers and microcrystalline pharmaceutical substrates.
- Evaluate stabilizer performance through lyophilization and reconstitution cycles, including protein integrity before and after freeze-drying stress.
- Use analytical methods including nanoDSF, SEC, DLS, CD, UV and fluorescence spectroscopy, SDS-PAGE, and cIEF.
- Prepare reagents, buffers, and samples, and maintain accurate laboratory and electronic records.
- Collaborate with formulation scientists on laboratory planning, team meetings, and progress updates.
Requirements
- Currently enrolled in an accredited bachelor's or graduate degree program in biochemistry, biophysics, pharmaceutical sciences, chemical engineering, molecular biology, or a related field.
- Prior hands-on laboratory experience in an academic or industry setting.
- Knowledge of basic analytical techniques for protein characterization.
- Strong attention to detail, precise protocol execution, organization, and ability to manage multiple priorities.
- Effective written and verbal communication skills.
- Must be authorized to work in the United States and qualify as a U.S. person under applicable export-control requirements.
Nice to have
- Junior, senior, or graduate academic standing.
- Experience with DLS, nanoDSF, SEC, CD, capillary electrophoresis, protein formulation, biologics drug product development, or protein biochemistry.
- Familiarity with lyophilization, freeze-drying, tangential flow filtration, or related solid-state processing.
- Experience with GraphPad Prism, Python, MATLAB, or similar data analysis tools.
- GLP-compliant or structured R&D laboratory experience, or interest in space medicine and in-orbit manufacturing.
Culture & Benefits
- Collaborative startup environment with hands-on technical and professional learning.
- Interns receive a subset of the full-time employee benefits package.
- Housing stipend for interns relocating to the area and commuter benefit for local transportation.
- Company and team events, stocked kitchen, daily lunch, twice-weekly dinner, and complimentary EV charging.
- Full-time employee benefits include health coverage, paid holidays, PTO, retirement matching, and wellness support.
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