Postdoctoral Fellow (Protein Sciences)

TL;DR

Postdoctoral Fellow (Protein Sciences): Investigating the structure and mechanism of action of critical protein complexes involved in DNA repair and RNA regulation with an accent on structural biology and biophysical characterization. Focus on utilizing X-ray crystallography and single-particle cryo-EM to uncover fundamental biological mechanisms for drug discovery.

Location: South San Francisco, California, United States

Salary: $100,000 – $106,500

Company

hirify.global, a member of the Roche group, is a pioneer of the biotechnology industry dedicated to discovering and developing medicines for serious and life-threatening diseases.

What you will do

• Investigate the structure and mechanism of action of critical protein complexes involved in DNA repair and RNA regulation.
• Develop and lead independent research projects from day one.
• Utilize state-of-the-art facilities, including Titan Krios and Glacios microscopes and high-performance computer clusters.
• Conduct high-impact research to advance the understanding of human physiology in health and disease.
• Publish findings in top peer-reviewed journals as part of the post-doctoral training program.

Requirements

• Ph.D. in structural biology, biochemistry, molecular biology, or a related field (or scheduled to receive by 2026).
• Expertise in protein purification and biophysical characterization.
• Proven experience in structure determination of multi-protein complexes using X-ray crystallography and/or single-particle cryo-EM.
• Strong record of first-author publications in top peer-reviewed journals.
• Strong oral and written communication skills.

Nice to have

• Experience in protein engineering.
• Proficiency in biophysical characterization methods for protein-protein interactions, such as SPR or BLI.

Culture & Benefits

• Competitive salaries and fully funded research expenses.
• Access to world-leading research facilities and a scientifically stimulating environment.
• Mentorship and support to develop into an independent scientist and leader.
• Professional development through world-class seminars and networking workshops.
• Relocation benefits are available for this position.