Senior Project Manager, Biologics R&D – Lead Program (Biologics R&D)

Location: On-site in South San Francisco, California, United States; remote candidates will not be considered.

Base salary: $148,000–$185,000 annually, plus bonus and equity.

Company

hirify.global is a biotech startup using generative AI and foundation models for biology to develop protein and antibody therapeutics and improve drug discovery and development.

What you will do

• Own day-to-day planning and execution for a lead T-cell engager program from late-stage research through development candidate nomination and IND-enabling studies.
• Build and maintain integrated timelines covering research, nonclinical, CMC, regulatory workstreams, critical paths, milestones, dependencies, and deliverables.
• Partner with scientific and functional leads to define decisive experiments, pressure-test assumptions, and prepare go/no-go decision packages.
• Coordinate cross-functional meetings, document decisions, track action items, and resolve interdependencies across workstreams.
• Manage outsourced CRO and CDMO activities, including GLP toxicology, cell line development, process development, timeline integration, and issue escalation.
• Own risk management, scenario planning, resource coordination, budget tracking, and spend forecasting.

Requirements

• 6+ years of industry experience in biologics R&D, including 3+ years in project or program management with ownership of integrated program plans.
• Experience managing antibody or protein therapeutic programs from research through development candidate nomination and IND-enabling studies.
• Working fluency in nonclinical development, CMC, cell line development, process development, developability, and regulatory activities.
• Experience managing outsourced work with CROs and/or CDMOs.
• Strong analytical, planning, organizational, communication, collaboration, and stakeholder management skills.
• Ability and willingness to work on-site in the South San Francisco office.

Nice to have

• Advanced degree in life sciences or a related field.
• Experience with T-cell engagers, bispecific antibodies, or other immuno-oncology biologics.
• Completed IND filing experience.
• PMP, CAPM, or PMI-ACP certification.
• Experience working in a fast-paced startup environment and leading without authority.

Culture & Benefits

• Open, flexible, and collaborative work environment.
• Competitive compensation and benefits package.
• Base salary plus bonus and equity.
• Opportunity to contribute to innovative biologics development and improved patient outcomes.