4 дня назад
Senior Scientist - Precision Oncology
127 122 - 171 988$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Senior Scientist - Precision Oncology (Cancer Biology/CRISPR): Designing and executing studies to validate oncology targets, test therapeutic hypotheses, and define mechanisms of action in cancer-relevant models with an accent on cancer cell biology, mechanistic pharmacology, genome engineering, and quantitative assay development. Focus on applying advanced CRISPR technologies, high-content imaging, high-throughput assays, and AI tools while translating complex biological data into oncology drug discovery programs.
Location: US - California - Thousand Oaks
Salary: USD 127,121.75–171,988.25 annual
Company
is a biotechnology company researching, manufacturing, and delivering medicines for serious illnesses, including cancer, rare diseases, inflammatory conditions, and cardiometabolic conditions.
What you will do
- Design and execute studies to validate oncology targets, test therapeutic hypotheses, and define mechanisms of action in cancer-relevant models.
- Apply advanced CRISPR genome-editing technologies to establish target function and genetic dependencies.
- Evaluate emerging technologies and AI tools that can accelerate oncology discovery.
- Develop quantitative assays for target engagement, pathway modulation, protein function, protein-complex biology, and small-molecule mechanisms of action.
- Analyze complex data and communicate biological insights to multidisciplinary discovery and leadership teams.
- Collaborate with biology, chemistry, computational sciences, pharmacology, and translational sciences teams.
Requirements
- Doctorate degree, or a master’s degree with 2 years of scientific experience, or a bachelor’s degree with 4 years of scientific experience.
- Ph.D. in cancer biology, cell biology, molecular biology, genetics, chemical biology, or a related discipline, plus 1–3 years of relevant postdoctoral or industry research experience.
- Strong expertise in cancer cell biology, cell signaling, mechanistic pharmacology, and small-molecule oncology drug discovery.
- Subject matter expertise in advanced CRISPR technologies and genome engineering.
- Experience with advanced imaging, high-throughput cellular and biochemical assays, quantitative analysis, automation-compatible workflows, and quality control.
- Strong experimental design, data analysis, troubleshooting, communication, collaboration, creativity, and innovation skills.
Culture & Benefits
- Collaborative, innovative, science-based research environment.
- Health, dental, vision, life, disability, and flexible spending benefits.
- Retirement and savings plan with company contributions.
- Discretionary annual bonus and stock-based long-term incentives.
- Paid time-off plans and career development opportunities.
- Flexible work models where applicable.
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