Senior Director of Program Management (Gene Therapy)

Location: Hybrid role based out of the San Diego, California office; remote work is available most of the time with in-person collaboration, and candidates outside the area must be willing to travel as needed. Domestic and international travel of approximately 20–30% is required.

Salary: $214,000–$292,000 annual.

Company

hirify.global is a global biopharmaceutical company developing treatments for patients with serious and rare diseases.

What you will do

• Serve as the operational COO for the Global Program Team and lead strategy execution across late-stage gene therapy programs.
• Direct integrated program planning, budgets, risks, timelines, resources, documentation, dashboards, and stakeholder communications.
• Lead programs through pivotal trials, regulatory submissions, approval, and commercial launch.
• Coordinate Regulatory Affairs, Medical Affairs, Market Access, Commercial, Supply Chain, and other functions to drive launch readiness.
• Manage scenario planning and gene therapy-specific risks, including vector manufacturing, batch release, immunogenicity, long-term follow-up, and health authority interactions.
• Mentor program management professionals and improve PMO processes, standards, and operating structures.

Requirements

• Bachelor’s degree in a scientific or medical discipline.
• 12+ years of program or project management experience, including leadership in late-stage R&D within a biotech or biopharmaceutical environment.
• Required hands-on experience with gene therapy, preferably viral-vector modalities such as AAV or lentiviral therapies, or with biologics.
• Required experience directly supporting or leading at least one successful commercial product launch.
• Required formal experience mentoring junior program management professionals in a matrixed environment.
• Strong scientific, cross-functional leadership, regulatory, communication, and program governance skills; PMP certification is a plus.

Nice to have

• Advanced degree such as Ph.D., Pharm.D., M.D., or M.S.
• Experience in neurology or rare diseases.
• Knowledge of Orphan Drug Designation, Breakthrough Therapy, Accelerated Approval, and other expedited regulatory pathways.
• Experience with tools such as MS Project, Excel, PowerPoint, SharePoint, or Veeva.

Culture & Benefits

• Purpose-driven environment focused on transforming the lives of patients with serious and rare diseases.
• Medical, dental, vision, mental health, wellbeing reimbursement, and Employee Assistance Program benefits.
• Paid time off, fertility and family-forming benefits, caregiver support, and flexible work schedules.
• 401(k) with company match, annual equity awards, ESPP, and company-paid life and disability insurance.
• Learning programs, mentorship connections, employee resource groups, and service opportunities.