3 дня назад
Protein/Enzyme Chemist RA 3 (Protein Biochemistry)
71 000 - 103 700$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Protein/Enzyme Chemist RA 3 (Protein Biochemistry): Developing and transferring robust protein purification processes and assay systems for diagnostic reagents with an accent on chromatography, buffer formulation, protein characterization, and process robustness. Focus on optimizing scalable manufacturing processes, troubleshooting complex results, and presenting analytical findings to guide design decisions.
Location: San Diego, California, United States
Annual base salary: $71,000–$103,700, plus bonus eligibility.
Company
develops diagnostic technologies and products focused on women’s health.
What you will do
- Develop robust, scalable protein purification processes for transfer to manufacturing.
- Purify proteins using column chromatography and filtration techniques.
- Perform functional and physical assays to evaluate protein purity and stability.
- Develop and verify buffer systems for specific protein design requirements.
- Document experiments, curate samples, and prepare process development reports.
- Troubleshoot results, stress-test processes, and present findings to team leaders.
Requirements
- BS with 3–5 years of post-baccalaureate laboratory experience, or equivalent post-M.S. experience, in biochemistry, molecular biology, microbiology, chemistry, chemical engineering, biomedical engineering, or a related field.
- Experience analyzing proteins and nucleic acids using SDS-PAGE, agarose gel electrophoresis, UV/Vis spectroscopy, fluorescence-based activity assays, or quantitation methods.
- Experience performing PCR assays with fluorescent intercalating dyes or hydrolysis probes.
- Familiarity with IMAC, affinity, ion exchange, hydrophobic interaction, or size exclusion chromatography.
- Experience formulating protein buffers and understanding salts, chelators, biological buffers, and reducing agents.
- Experience with specification setting, method development and transfer, formal risk assessments, and enterprise tools such as SAP, Oracle, Agile, Microsoft Office, and JMP.
Culture & Benefits
- Collaborative work with applied research scientists and operations partners.
- Training and continued professional development throughout the career.
- Work focused on diagnostic assays and technologies designed to support earlier and more certain detection of health conditions.
- Equal opportunity employment environment.
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