13 часов назад
Postdoctoral Research Fellow (BioMedicine Design)
64 600 - 107 600$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Postdoctoral Research Fellow (BioMedicine Design): Developing a next-generation T cell engager to improve tumor selectivity and minimize on-target, off-tumor toxicity with an accent on protein engineering, cell biology, immunology, and preclinical evaluation. Focus on designing molecular constructs, developing cell-based assays, screening and ranking molecules, and analyzing data to guide early-stage therapeutic discovery.
Location: San Diego, California, United States; on-premise work required. Candidates must have permanent authorization to work in the United States.
Annual base salary: $64,600–$107,600, plus eligibility for a 7.5% bonus target.
Company
's BioMedicine Design group develops innovative biotherapeutics and next-generation therapeutic modalities.
What you will do
- Develop a next-generation T cell engager designed to improve tumor selectivity and reduce on-target, off-tumor toxicity.
- Design and produce molecular constructs to investigate biology and mechanisms of action.
- Develop and use cell-based assays to test hypotheses and screen and rank molecules.
- Conduct literature research, identify knowledge gaps, and form experimentally testable hypotheses.
- Communicate results at internal meetings and make data-driven decisions about research direction.
- Collaborate with interdisciplinary research teams to discover and optimize novel therapeutics.
Requirements
- PhD in cancer biology, immunology, molecular or cellular biology, biochemistry, chemical and biomolecular engineering, or a related discipline.
- Two letters of recommendation are required, including one from a PI and one from an additional professor.
- Commitment to a fixed-term, full-time postdoctoral fellowship lasting 2–4 years, with less than two years of postdoctoral experience.
- At least one first-author scientific research article in a high-quality specialty or general readership journal.
- Experience with molecular and cell biology techniques, including construct design, molecular cloning, recombinant protein expression and purification, mammalian cell culture, cell line engineering, transfection, cell-based assays, and flow cytometry.
- Strong data analysis, planning, organizational, problem-solving, analytical, written, and oral communication skills.
Nice to have
- Experience with antibody discovery, protein engineering, or display technologies such as yeast or phage display.
- Experience with bispecific antibodies or T cell engagers.
Culture & Benefits
- Collaborative work with diverse research teams across .
- Training at the intersection of protein engineering, cell biology, and immunology.
- Opportunities to publish in high-impact journals and build expertise in antibody discovery, cellular assays, and preclinical evaluation.
- Benefits include a 401(k) with matching and retirement contributions, paid vacation and leave, and medical, prescription, dental, and vision coverage.
- U.S. work visa sponsorship is not available now or in the future.
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