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4 дня назад

Associate Scientist, Advanced Characterization (Biotech)

121 892 - 135 435$
Формат работы
onsite
Тип работы
fulltime
Грейд
junior
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

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TL;DR
Associate Scientist, Advanced Characterization (Biotech): Designing and analyzing high-throughput SPR- and BLI-based biosensor assays to characterize antibody and peptide interactions with target proteins, with an accent on binding kinetics, affinity measurements, and epitope binning. Focus on interpreting biomolecular interaction data, optimizing kinetic assays, qualifying proteins through QC workflows, and guiding clone advancement decisions across cross-functional drug discovery projects.

Location: Onsite at the Emeryville headquarters, United States. No travel is required; office hours are 8am-5pm PT.

Annual base salary: $121,892–$135,435, plus target bonus, equity, and other rewards.

Company

hirify.global provides antibody repertoires and screening technologies for pharmaceutical partners developing next-generation therapeutics, including antibody, ion channel, and transporter discovery.

What you will do

  • Design, execute, and analyze SPR- and BLI-based assays for antibody and peptide interactions with target proteins.
  • Develop and optimize kinetic and epitope binning assays to support clone selection.
  • Collaborate with Screening, Molecular Biology, Bioinformatics, Bioassays, and antibody discovery teams to interpret binding data and guide advancement decisions.
  • Plan experiments, troubleshoot studies, and maintain protocols, SOPs, and experimental reports.
  • Present findings in internal meetings and contribute to scientific presentations, posters, and publications.
  • Perform protein QC and purification, including SDS-PAGE, analytical SEC, and preparative SEC.

Requirements

  • PhD in Biochemistry, Molecular Biology, Biophysics, or a related field with 0+ years of experience; alternatively, an MSc with 7+ years or a BSc with 10+ years of relevant experience.
  • Expertise in protein biochemistry and biomolecular interaction analysis.
  • Understanding of dose-dependent binding assays, binding affinity, avidity, and the Langmuir 1:1 binding model.
  • Practical experience with SPR platforms such as Biacore or Carterra and/or BLI platforms such as Octet.
  • Experience with data visualization and interpretation, plus the ability to work independently and collaboratively in a fast-paced environment.
  • Strong communication skills and the ability to explain scientific findings to non-specialist audiences.

Nice to have

  • Wet-lab experience in protein purification and QC, including aSEC and SDS-PAGE.
  • Experience with ITC, FRET, stopped-flow fluorescence, or enzyme kinetics.
  • Structural biology experience.
  • Contributions to scientific publications or patents.

Culture & Benefits

  • Collaborative, innovative, and cross-functional scientific environment.
  • Comprehensive health plans, immediate 401(k) matching, PTO, sick leave, and paid parental leave.
  • Target bonus, equity, refresh grants, and ESPP.
  • Commuter benefits, wellness stipend, and education reimbursement.
  • Inclusive workplace and equal opportunity employment.

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