Lead In Vivo Researcher (Therapeutic Genome Engineering)

Location: Memphis, Tennessee, United States

Salary: $60,320–$105,040 per year

Company

hirify.global conducts translational biomedical research focused on pediatric catastrophic diseases and transformative treatments.

What you will do

• Lead complex in vivo studies using humanized, immunocompromised, hemoglobinopathy, and other disease-relevant research models.
• Isolate, characterize, prepare, engraft, and maintain human hematopoietic stem cells and targeted cell populations.
• Administer experimental genome-engineering therapies using precise, minimally invasive delivery methods.
• Perform aseptic sample collection, dosing, molecular analysis, and downstream flow cytometry studies.
• Maintain detailed health, engraftment, experimental, and observational records.
• Mentor early-career researchers and contribute to the optimization of in vivo methods and cellular assays.

Requirements

• Bachelor’s degree in a relevant scientific field is required; a master’s degree or higher is strongly preferred.
• At least 5 years of research experience, or 3 years with a master’s degree; no prior experience is required with a PhD.
• Demonstrated expertise with humanized research models, highly immunocompromised strains such as NBSGW, and/or disease models such as Townes.
• Hands-on proficiency with multicolor flow cytometry and Magnetic-Activated Cell Sorting (MACS).
• Experience handling, preparing, and delivering or transplanting human hematopoietic stem cells is highly preferred.
• Knowledge of animal welfare, regulatory compliance, protocol refinement, research databases, and flow cytometry analysis software.

Culture & Benefits

• Research practices follow the principles of Replacement, Reduction, and Refinement (3Rs).
• Work closely with veterinary staff, Animal Resource Center personnel, and research teams.
• Apply humane endpoints, environmental enrichment, and welfare-focused handling techniques.
• Follow institutional policies, the ILAR Guide for the Care and Use of Laboratory Animals, and the USDA Animal Welfare Act.
• Full-time employment with benefits available through St. Jude.