9 дней назад
Senior Scientist, Cell Production & Tissue Engineering (iPS Cells)
127 500 - 170 000$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Senior Scientist, Cell Production & Tissue Engineering (iPS Cells): Developing and scaling production, differentiation, and functional maturation methods for iPS-derived renal cells supporting tissue-engineered kidney grafts with an accent on cell reprogramming, physiological assays, analytical characterization, and GMP readiness. Focus on designing sophisticated experiments, transferring technologies into manufacturing processes, and mentoring scientists while advancing 3D-printed organ therapeutics.
Location: 100% onsite in Medford, Massachusetts, United States
Salary: $127,500–$170,000 per year
Company
is a public benefit biotechnology and pharmaceutical company developing therapies for rare diseases and technologies to expand the availability of transplantable organs, including bioartificial kidneys.
What you will do
- Lead development and implementation of production methods for primary and iPS-derived renal cells.
- Develop maturation methods and physiological in-vitro assays for iPS-derived renal cell function.
- Lead internal and external cell production activities supporting advanced organ therapeutics.
- Develop analytical methods to characterize cells used in 3D-printed organs.
- Design, execute, and oversee complex experiments, projects, protocols, and laboratory methods.
- Collaborate with manufacturing, academic, and industry partners to evaluate technologies, transfer processes, and advance methods toward GMP readiness.
Requirements
- Bachelor’s, Master’s, or PhD in biomedical engineering, cell biology, molecular biology, or a related discipline.
- Relevant experience: 10+ years with a bachelor’s degree, 8+ years with a master’s degree, or 5+ years with a PhD, including stem cell differentiation, reprogramming, bioreactor scale-up, regenerative medicine, or tissue engineering.
- Technical expertise in iPS reprogramming, expansion, and differentiation methods.
- Ability to formulate hypotheses, design technically challenging experiments, analyze multidimensional data, and communicate scientific conclusions.
- Experience with laboratory instrumentation and data software, plus advanced written and oral communication skills.
- Ability to mentor and motivate team members; the role may include team management responsibilities.
Nice to have
- Experience differentiating iPSCs into endothelial and renal epithelial cells.
- Experience with automated cell-processing equipment such as CliniMACS Plus, FACS, LOVO, Cue, Sepax, Sefia, and Rotea.
- Knowledge of transferring R&D cell-expansion methods to GMP.
- Experience with Ambr and vertical-wheel bioreactors at scales up to 10L+.
Culture & Benefits
- Collaborative environment spanning internal research, manufacturing, academic, and industry partnerships.
- Work focused on developing tissue-engineered kidney grafts and treatments for end-stage renal disease.
- Eligible employees may receive medical, dental, vision, prescription, wellness, savings, 401(k), ESPP, paid time off, parental leave, and disability benefits.
- Opportunities to contribute to scientific publications, conference presentations, patents, and regulatory filings.
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