Principal Software Engineer (AI/.NET)

Location: Mansfield, Massachusetts, United States — hybrid

Salary: $152,000–$190,000 USD per year

Company

hirify.global develops elluminate®, a clinical data cloud that helps life sciences organizations unify, analyze, and use data across the clinical trial lifecycle.

What you will do

• Design, develop, test, and deploy scalable, secure, interactive web applications.
• Own core platform modules from concept through release and production support.
• Influence application and system architecture with emphasis on performance, reliability, security, and maintainability.
• Integrate LLMs and AI services into .NET- and Python-based products, including copilots, intelligent automation, and agentic workflows.
• Lead design reviews, mentor engineers, collaborate with Product Management and QA, and contribute to technical documentation.
• Diagnose complex production issues across distributed systems and ensure compliance with quality standards and applicable regulations.

Requirements

• Bachelor’s or Master’s degree in Computer Science or equivalent practical experience.
• 10+ years of software design and development experience, preferably with the Microsoft technology stack.
• Expert proficiency in C#, .NET, and ASP.NET MVC/Web APIs.
• Strong full-stack web development experience with Angular, TypeScript, HTML, and CSS.
• Hands-on experience integrating LLM-based services such as OpenAI or Azure OpenAI, using Python and/or .NET.
• Strong software design, SDLC, communication, documentation, and technical leadership skills.

Nice to have

• Strong Microsoft SQL Server expertise, including performance tuning.
• Experience with microservices, distributed systems, and cloud platforms, preferably AWS.
• Secure development experience and knowledge of common vulnerabilities and mitigations.
• Experience with clinical trial data, life sciences, regulated SaaS, data visualization, or analytics-driven user experiences.
• Familiarity with agent-based or workflow-driven AI architectures.

Culture & Benefits

• People-first, inclusive culture focused on diversity and individual contribution.
• Opportunities for learning, growth, and continuous improvement.
• Company-approved AI tools may be used to improve productivity and quality, subject to confidentiality, validation, and responsible-use policies.
• Recognized with the 2025 Top Workplaces USA Award for Remote Work and additional culture and work-life-balance awards.
• Equal opportunity workplace committed to employment decisions based on qualifications, merit, culture fit, and business needs.