Scientist – Erythroid Biology (siRNA)

Location: Thousand Oaks, California, United States

Annual salary: $115,393.45–$156,120.55

Company

Biotechnology company developing medicines for serious illnesses across oncology, inflammation, general medicine, and rare disease.

What you will do

• Design and execute in vitro and ex vivo assays evaluating siRNA delivery and function.
• Develop human primary cell-based systems for erythroid biology research.
• Support target validation and mechanism-of-action studies for siRNA therapeutics.
• Establish and optimize multi-color flow cytometry panels and qPCR/RNA-based readouts.
• Contribute to IND-enabling studies and related data packages.
• Prepare technical reports, protocols, and study summaries, and present results to project teams.

Requirements

• Doctorate degree, or a master’s degree plus 2 years of scientific experience, or a bachelor’s degree plus 4 years of scientific experience.
• Experience with siRNA or RNA therapeutics, including delivery or functional assays.
• Background in erythroid biology and hematopoiesis.
• Strong experience with multi-color flow cytometry and cell-based functional assays.
• Familiarity with gene expression, qPCR, RNA assays, and target engagement assays.
• Experience collaborating in cross-functional drug discovery teams.

Nice to have

• Knowledge of hemoglobinopathies, conjugated delivery systems, CRISPR, or gene editing.

Culture & Benefits

• Collaborative, innovative, and science-based work environment.
• Health, dental, and vision coverage, life and disability insurance, and flexible spending accounts.
• Retirement and savings plan with company contributions.
• Annual discretionary bonus program and stock-based long-term incentives.
• Paid time-off plans and career development opportunities.
• Flexible work models where applicable to the work location type.