1 день назад
Sr. Research Associate/Associate Scientist, Nonclinical Development (Biotechnology)
108 000 - 150 000$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Sr. Research Associate/Associate Scientist, Nonclinical Development (Biotechnology): Coordinating and executing in vivo and ex vivo nonclinical studies for immune-cell and gene-therapy platforms with an accent on murine oncology and immunology models, efficacy, pharmacokinetic/pharmacodynamic, and safety assessments. Focus on establishing xenograft models, performing necropsies and tissue processing, analyzing pharmacologic activity, and troubleshooting study execution with cross-functional teams and external research organizations.
Location: Redwood City, California, United States; onsite at least three days per week, with Tuesday–Thursday mandatory.
Salary: $108,000–$150,000 USD annually
Company
is a clinical-stage biotechnology company developing allogeneic gamma delta T-cell therapies for autoimmune diseases and cancer.
What you will do
- Coordinate and execute in vivo and ex vivo nonclinical studies evaluating immune-cell and gene-therapy platforms.
- Support efficacy, pharmacokinetic/pharmacodynamic, and safety assessments in murine oncology and immunology models.
- Contribute to study design, experimental planning, timelines, and data-driven program decisions.
- Coordinate study execution with cross-functional teams and external contract research organizations, troubleshooting technical challenges.
- Perform mouse necropsies and process tissues for flow cytometry, qPCR/ddPCR, ELISA, and mechanism-of-action analyses.
- Maintain complete and organized experimental records in accordance with internal quality standards.
Requirements
- Bachelor’s degree in biological sciences or a related field with 5+ years of relevant R&D experience, or a master’s degree with 3+ years of experience.
- Industry experience designing, executing, analyzing, and interpreting in vivo studies using murine xenograft or humanized immunology models, preferably in immuno-oncology.
- Experience administering therapeutic agents and establishing xenograft models through intravenous, intraperitoneal, and subcutaneous routes in mice.
- Proficiency in blood collection, tissue necropsy, and sample processing for flow cytometry.
- Experience with aseptic mammalian cell culture and preparation of human cancer cell lines for in vivo studies.
- Hands-on experience with in vivo bioluminescence or fluorescence imaging using IVIS platforms, plus strong data-analysis, communication, and documentation skills.
Nice to have
- Experience with flow cytometry, ELISA, qPCR/ddPCR, and cytokine bead-based assays.
Culture & Benefits
- Collaborative, high-performing research environment with a focus on in-person engagement.
- Annual cash bonus, equity incentives, employee stock purchase plan, and 401(k) with a company match.
- Medical, dental, vision, FSA, HSA, life, disability, legal, pet, and other insurance programs.
- Paid time off, company holidays, winter break, sick time, and paid parental leave.
- Onsite gym and fitness options, parking with electric vehicle charging, Caltrain shuttle, subsidized lunches, and stocked breakrooms.
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