Senior Scientist, Transplant Immunology & Gene Therapy

Location: 100% onsite in Silver Spring, Maryland, United States

Salary: $127,500–$170,000 per year

Company

hirify.global is a publicly traded biotech and pharmaceutical company developing therapies for rare diseases and technologies to expand the availability of transplantable organs.

What you will do

• Design and execute studies of innate and adaptive immune responses in donor and engineered lungs during ex vivo lung perfusion.
• Evaluate immunomodulatory strategies to improve lung preservation, reduce inflammation, and enhance post-transplant outcomes.
• Support lung-directed gene delivery using AAV, lentiviral, adenoviral, mRNA/LNP, and other platforms.
• Characterize immune cells and inflammatory pathways using flow cytometry, cytokine assays, transcriptomics, and histology.
• Develop molecular and functional assays and support preclinical transplant studies, data interpretation, and IND-enabling work.
• Collaborate with device, manufacturing, analytical, translational, and regulatory teams; mentor junior scientists and contribute to scientific publications and presentations.

Requirements

• Master’s degree in immunology, transplant biology, molecular biology, pulmonary biology, gene therapy, or a related field.
• 8+ years of related biotech or pharmaceutical industry experience with a Master’s degree, or 5+ years with a PhD.
• Strong background in immunology, including immune cell biology, inflammatory signaling, or transplant immunology.
• Experience with viral vector or non-viral gene delivery platforms and immunologic or molecular assay development.
• Strong experimental design, data analysis, communication, organization, and problem-solving skills.
• Ability to work independently and in multidisciplinary teams and to mentor team members.

Nice to have

• PhD in immunology, transplant biology, pulmonary biology, gene therapy, or a related field.
• Experience with lung transplantation, ex vivo lung perfusion, thoracic organ preservation, or immune modulation.
• Experience with pulmonary or transplant gene therapy, cell or gene therapy development, human tissue, or translational preclinical models.
• Familiarity with IND-enabling studies and regulatory interactions.

Culture & Benefits

• Mission-driven work focused on rare diseases and increasing the availability of transplantable organs.
• Medical, dental, vision, prescription, wellness, savings, 401(k), and ESPP programs for eligible employees.
• Paid time off, paid parental leave, and disability benefits for eligible employees.
• Fast-paced translational environment with cross-functional scientific collaboration.