9 дней назад
Senior Scientist – Functional Genomics (Genome Engineering)
127 122 - 171 988$
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Senior Scientist – Functional Genomics (Genome Engineering): Developing and applying viral vector platforms and genome engineering technologies to accelerate therapeutic target discovery, validation, and mechanistic studies with an accent on AAV and lentiviral vector engineering, CRISPR-based perturbation, and functional genomics. Focus on designing and analyzing in vitro and in vivo experiments, implementing emerging technologies, and solving challenging biological problems with multidisciplinary research teams.
Location: Thousand Oaks, California, United States; onsite research role
Annual salary: USD 127,121.75–171,988.25
Company
is a biotechnology company researching, manufacturing, and delivering medicines across oncology, inflammation, general medicine, and rare disease.
What you will do
- Develop next-generation viral vector platforms and genome engineering technologies for functional genomics and therapeutic target discovery.
- Design, engineer, produce, optimize, and characterize AAV and lentiviral vectors for gene overexpression and CRISPR-based genetic perturbation.
- Execute molecular biology and functional genomics experiments in in vitro and in vivo model systems.
- Analyze and interpret experimental data, communicating biological insights to multidisciplinary discovery teams.
- Evaluate emerging genome engineering, viral vector engineering, and functional genomics technologies.
- Collaborate with biology, computational biology, chemistry, and therapeutic area scientists.
Requirements
- Doctorate degree with relevant postdoctoral experience where applicable, or a master's degree with 3 years of scientific experience, or a bachelor's degree with 5 years of scientific experience.
- Background in molecular biology, genome engineering, CRISPR technologies, and functional genomics.
- Expertise in designing, engineering, producing, optimizing, and characterizing AAV and/or lentiviral vectors.
- Experience with viral vector technologies for in vitro and in vivo CRISPR-based genetic perturbation studies.
- Expertise in molecular cloning, construct design, and genetic tool development.
- Strong experimental design, data analysis, troubleshooting, communication, collaboration, creativity, and innovation skills.
Nice to have
- Ph.D. in molecular biology, cell biology, genetics, bioengineering, virology, or a related discipline.
- 1–2 years of relevant postdoctoral and/or industry research experience.
Culture & Benefits
- Collaborative, innovative, and science-based research environment.
- Health, dental, vision, life, disability, and flexible spending benefits.
- Retirement and savings plan with company contributions.
- Annual bonus program and stock-based long-term incentives.
- Award-winning time-off plans and career development opportunities.
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