Senior Director, HEOR & Evidence Strategy (Biotech)

Location: Remote; Cambridge, MA, United States

Salary: $289,601–$353,957 USD per year, plus performance-based annual bonus and equity compensation

Company

hirify.global Therapeutics develops gene editing treatments for rare and serious diseases, including hereditary angioedema and transthyretin amyloidosis.

What you will do

• Own integrated evidence generation plans across programs and align HEOR strategy with clinical development, medical affairs, commercial, and market access objectives.
• Develop evidence frameworks, value narratives, global value dossiers, AMCP dossiers, payer decks, and health technology assessment submissions.
• Direct cost-effectiveness models, budget impact models, scenario analyses, and innovative access or value-based agreement designs.
• Lead real-world evidence, outcomes research, patient-reported outcomes, quality-of-life initiatives, and long-term durability assessments.
• Build and manage the Field HEOR team and lead payer-facing engagements across commercial, Medicare, and Medicaid segments.
• Translate payer insights into evidence plans, model assumptions, coverage strategies, and utilization management approaches.

Requirements

• 10+ years of experience in HEOR, market access, or payer strategy within the pharmaceutical or biotech industry.
• At least 5 years of payer-facing HEOR or Field HEOR experience, including direct engagement with payers and presentation of clinical and economic evidence.
• Strong knowledge of payer decision-making, health economics methodologies, reimbursement systems, medical policy, and evidence needs for high-cost specialty or gene therapies.
• Experience developing or deploying payer launch deliverables and driving real-world evidence projects.
• Advanced degree such as MPH, PhD, PharmD, MD, or MS in health economics, outcomes research, public health, or a related field, plus a BS/BA.
• Up to 40% travel for partner meetings, conferences, and internal cross-functional workshops.

Nice to have

• Experience in rare disease, cell or gene therapy, or other advanced therapeutics.
• Experience supporting value-based contracting discussions.

Culture & Benefits

• Remote work arrangement with collaboration across clinical, regulatory, medical affairs, market access, and commercial functions.
• Performance-based annual cash bonus and new-hire equity grant.
• Eligibility for annual equity awards.
• Opportunity to build HEOR capabilities and processes in a fast-paced, build-from-scratch environment.