Senior Scientist II (Pharmacology) (Oncology)

Location: Alameda HQ, Alameda, California, United States; office-based role

Salary: $132,500–$188,000 annually, with the range varying by U.S. geographic market.

Company

hirify.global develops therapeutic candidates and supports oncology drug discovery and development programs.

What you will do

• Lead, design, execute, and interpret in vivo pharmacology studies covering PK, PD, and efficacy in rodent tumor models.
• Establish PK/PD/efficacy relationships and characterize toxicity profiles using preclinical animal models.
• Represent Pharmacology or serve as Project Team Co-Lead on Discovery project teams.
• Design and test drug-target hypotheses using scientific literature and internal datasets.
• Coordinate studies with contract research organizations and prepare pharmacology reports supporting IND filings.
• Support animal facility and laboratory operations, collaborate with IACUC, and ensure animal welfare compliance.

Requirements

• PhD in Pharmacology, Cancer Biology, Molecular and Cellular Biology, or a closely related field, plus at least two years of industrial experience after postdoctoral training, or equivalent experience.
• Deep knowledge of in vivo pharmacology for oncology drug discovery and extensive experience with xenograft, syngeneic, genetically engineered mouse, orthotopic, PDX, and humanized tumor models.
• Experience writing regulatory and IND filing documents for preclinical pharmacology.
• Expertise in experimental design, data analysis, cell culture with aseptic technique, animal handling, dosing, blood and tissue collection, necropsy, tumor measurement, and rodent survival surgery.
• Required understanding of IACUC and AAALAC regulations and guidelines.
• Managerial experience leading a small group of 3–5 people is required.

Nice to have

• Strong publication record and broad scientific expertise.
• Experience coaching junior scientists and working across multidisciplinary project teams.

Culture & Benefits

• Collaborative office environment focused on sharing ideas and solutions.
• Medical, dental, vision, life, disability, and flexible spending benefits.
• 401(k) plan with company contributions and eligibility for an annual discretionary bonus.
• Company stock purchase opportunities and long-term incentives.
• Fifteen vacation days in the first year, seventeen paid holidays, and up to ten sick days annually.
• Work may include weekends and holidays to support in vivo studies; equipment includes dual monitors and ergonomic chairs.