Scientist II (Downstream Processing)

Location: Waltham, Massachusetts, United States; laboratory-based role with occasional travel to company sites, collaborators, conferences, or customer locations.

Estimated base salary: $113,600–$163,300 per year, plus eligibility for variable cash compensation and, for eligible roles, equity.

Company

hirify.global develops bioprocessing technologies and solutions that support the production of biologic drugs and improve cost and process efficiency.

What you will do

• Design, plan, execute, and interpret laboratory studies for downstream processing technologies, equipment, consumables, and products.
• Generate application data for monoclonal antibodies, recombinant proteins, AAV and lentivirus vectors, vaccines, cell and gene therapies, and related modalities.
• Operate, program, and troubleshoot lab-scale chromatography systems, including AKTA systems, and TFF systems using hollow fibers and cassettes.
• Analyze experimental data, identify trends and limitations, and produce technical recommendations, reports, presentations, and application data packages.
• Collaborate with product development, product management, and field teams on product readiness, technical positioning, and adoption.
• Prepare and present findings through publications, conferences, posters, webinars, and other scientific communications.

Requirements

• Ph.D. in chemical engineering, biochemical engineering, biochemistry, biotechnology, biology, or a related discipline with 2+ years of relevant experience; alternatively, an M.S. with typically 5+ years or a B.S. with typically 8+ years of relevant industry experience.
• Strong understanding of downstream processing and unit operations, including chromatography, clarification, filtration, ultrafiltration/diafiltration, sterile filtration, and process analytical methods.
• Hands-on experience with ELISA, HPLC, SEC-MALS, SDS-PAGE, protein concentration assays, impurity assays, or related product quality and process performance analytics.
• Ability to independently design and execute experiments, troubleshoot significant technical issues, interpret complex data, and communicate recommendations clearly.
• Ability to work safely in a laboratory, handle chemicals and biological materials, use laboratory equipment, and lift or move materials up to 25 pounds.
• Ability to work independently and collaboratively in a fast-paced R&D environment, including occasional extended hours to meet project timelines.

Nice to have

• Experience evaluating bioprocessing technologies, equipment, or consumables in an industrial biotechnology, biopharmaceutical, or life sciences environment.
• Mammalian cell culture experience.

Culture & Benefits

• Safety-focused, quality-driven laboratory environment.
• Paid time off, health, dental, and vision coverage.
• Retirement benefits and flexible spending accounts.
• Variable cash programs, with equity available for eligible roles.