1 день назад
Associate Scientist - Therapeutic Proteins
70 300 - 110 100$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Associate Scientist - Therapeutic Proteins (Antibody Radioconjugates): Generating and characterizing radiolabeled and fluorescently conjugated antibody tracers for preclinical immunoPET and Cryo-fluorescence Tomography imaging with an accent on protein chemistry, bioconjugation, radiolabeling, and chromatographic quality control. Focus on preparing time-critical imaging tracers, validating binding in mammalian cell assays, and maintaining compliant radiation safety and laboratory records.
Location: Tarrytown, New York, United States — On-site
Salary: $70,300–$110,100 annually
Company
Develops life-changing medicines for people with serious diseases through science and innovation.
What you will do
- Perform antibody bioconjugation with bifunctional chelating agents such as DFO and DOTA, as well as fluorescent probes.
- Generate and characterize Zr-89, Cu-64, and other radiolabeled antibody tracers for preclinical imaging.
- Purify radiolabeled products and perform quality control using radio-HPLC, radio-iTLC, gamma counting, SE-HPLC, SDS-PAGE, Western blot, and UV/Vis spectroscopy.
- Maintain mammalian cell cultures and conduct cell-based assays to validate tracer binding and function.
- Coordinate tracer preparation timelines with imaging scientists and project teams across therapeutic areas.
- Maintain electronic laboratory notebooks, radiation safety records, instruments, supplies, and experimental documentation.
Requirements
- B.S. in Chemistry, Biochemistry, Chemical Engineering, Chemical Biology, or a related field, with 1–2 years of laboratory experience.
- Hands-on experience in protein chemistry and bioconjugation, or strong foundational knowledge with willingness to learn.
- Experience with HPLC, FPLC, or column chromatography and mammalian cell culture.
- Comfort working with radioactive materials and willingness to complete radiation safety training.
- Computer proficiency, including Excel, Prism, or similar data analysis software, and electronic laboratory notebook systems.
- Ability to lift 50 lbs and communicate effectively in a collaborative environment.
Culture & Benefits
- Collaborative, fast-paced laboratory environment focused on reliability, precision, and independent work after training.
- Inclusive workplace and equal opportunity employment.
- Benefits may include incentive plans, equity awards, retirement benefits, health and wellness programs, insurance, paid time off, and family support benefits.
- On-site work is expected because many roles are performed together in person.
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