Principal System Engineer (LIMS)

Location: Cambridge or Norwood, Massachusetts, United States; 70% in-office work model

Salary: $130,800–$209,400 per year; California range: $162,750–$187,250

Company

Moderna develops mRNA technologies and medicines, with a focus on scientific progress and transforming how medicines are created and delivered.

What you will do

• Serve as the senior system expert for the LabVantage LIMS solution.
• Lead and deploy small and medium-sized continuous improvement projects across laboratory systems.
• Support large cross-functional projects and collaborate with business stakeholders and internal digital teams.
• Design, develop, and implement integrations with MES, SAP, LIMS, and potentially eQMS.
• Provide Level 2/3 application support, including version control, upgrades, patching, deployments, and maintenance.
• Contribute to the integrated digital laboratory systems strategy, risk management, and demand management business cases.

Requirements

• At least 8 years of LabVantage LIMS development experience.
• Experience as a functional LIMS expert, preferably with LabVantage.
• Experience in a GxP environment with a focus on GMP, cGMP, and manufacturing operations.
• Understanding of computer systems validation practices and GAMP.
• Bachelor’s degree or equivalent training and relevant work experience.
• Only U.S. persons are eligible because the role involves access to U.S. export-controlled technology or data; visa sponsorship is not available.

Culture & Benefits

• In-person collaboration supported through a 70/30 work model.
• Healthcare and voluntary benefit programs.
• Fitness, mindfulness, and mental health resources.
• Family planning benefits, including fertility, adoption, and surrogacy support.
• Paid vacation, volunteer days, sabbatical, global recharge days, and year-end shutdown.
• Savings and investment programs, plus location-specific benefits.