14 часов назад
Senior Research Associate, Discovery Pharmacology (Aging Biology)
109 200 - 140 000$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Senior Research Associate, Discovery Pharmacology (Aging Biology) (AAV gene therapy and bioassays): Designing, automating, executing, and troubleshooting cellular, biochemical, and complex in vitro assays for drug discovery and development with an accent on mammalian cell culture, AAV transduction, genome titration, transgene expression, and protein analysis. Focus on standardizing assay protocols, authoring SOPs, analyzing and presenting reproducible data, and advancing therapeutic programs in aging and cellular rejuvenation biology.
Location: San Francisco Bay Area, California, United States
Salary: $109,200–$140,000 per year for the Redwood City location.
Company
develops cell rejuvenation-based therapeutics intended to restore cellular health and resilience and address disease, injury, and age-related disabilities.
What you will do
- Support drug discovery and development projects across a diverse therapeutic portfolio.
- Culture and maintain mammalian cells, manage reagents and working stocks, and contribute to laboratory maintenance.
- Design, optimize, automate, execute, and troubleshoot cellular, biochemical, and complex in vitro bioassays.
- Standardize assay protocols, optimize methods, and draft assay SOPs.
- Document experimental methods, raw data, and results in an electronic laboratory notebook while ensuring reproducibility and data integrity.
- Present assay data at project team meetings to support scientific decision-making.
Requirements
- BS or MS in Molecular Biology, Cell Biology, Biochemistry, Bioengineering, or a related discipline.
- At least 5 years of industry experience in drug discovery and/or development.
- Expertise in AAV gene therapy cellular transduction assays, aseptic technique, genome titration, transgene expression, and protein analysis.
- Hands-on experience with qPCR, ddPCR, RT-qPCR, Western blot, ELISA, capillary electrophoresis, MSD, HTRF, AlphaLISA, and Luminex.
- Experience with laboratory automation instruments and platforms such as Bravo, Echo, I.DOT, and digital dispensers.
- Strong data analysis, statistical, documentation, communication, organization, and multitasking skills.
Nice to have
- Experience with viral gene therapy, mRNA-LNP, other nucleic acid therapeutics, and small molecules.
- Background in aging or rejuvenation biology.
- Familiarity with assay qualification criteria, processes, and SOP authoring.
Culture & Benefits
- Collaborative environment focused on scientific excellence and open communication.
- Commitment to belonging, diversity, and inclusion.
- Opportunity to contribute to cellular rejuvenation research and the development of new therapeutics.
- Approximately 80% of the role is dedicated to benchtop science.
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