4 часа назад
Sr. Research Associate - Gene Therapy (AAV)
96 172 - 116 236$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Sr. Research Associate - Gene Therapy (AAV): Processing and analyzing tissues from in vivo studies while developing and characterizing muscle AAV capsids and capsid libraries with an accent on molecular measurements, histology, and cell-based experiments. Focus on optimizing tissue-processing workflows, preparing qPCR and sequencing assays, analyzing experimental data, and troubleshooting complex biological protocols.
Location: Watertown, Massachusetts, United States
Base salary: $96,172.08–$116,236.54 per year
Company
develops genetic technologies and AI-driven solutions for gene therapy, bringing together molecular biology, protein engineering, software, data science, and machine learning.
What you will do
- Process, inventory, and dissect mammalian, mouse, and non-human primate tissues from in vivo studies.
- Extract, purify, enrich, and quantify nucleic acids using qPCR and RT-qPCR.
- Prepare amplicon next-generation sequencing libraries and perform quality-control steps.
- Support histology workflows, including tissue preparation, sectioning, staining, imaging, and analysis.
- Maintain mammalian cell cultures and run cell-based experiments to characterize muscle AAV capsids and capsid libraries.
- Analyze data, troubleshoot technical issues, document results in ELN and LIMS systems, and collaborate with experimental and computational teams.
Requirements
- BS or MS in biology, biochemistry, biomedical engineering, or a related field.
- At least 3 years of post-graduate, full-time hands-on wet-lab experience.
- Experience with DNA/RNA purification and analysis, including qPCR or RT-qPCR.
- Experience handling mammalian tissues or other complex biological samples.
- Ability to execute complex protocols accurately, organize large sample sets, and maintain detailed experimental records.
- Proactive problem-solving approach, strong data-analysis skills, willingness to use AI, and alignment with a high-expectation research environment.
Nice to have
- Experience with AAV biology, gene therapy, viral vectors, or drug-delivery technologies.
- Experience with next-generation sequencing library preparation and animal-tissue molecular measurements.
- Experience with histology workflows and quantitative analysis.
- Familiarity with ELN-LIMS software such as Benchling.
Culture & Benefits
- Mission-driven, high-trust environment focused on AI and genetic medicine.
- Annual performance-based bonus and stock options.
- Medical, dental, and vision coverage.
- 401(k) plan, flexible paid time off, and holidays.
- On-campus gym membership, onsite lunch, commuter support, and a company-provided laptop.
Hiring process
- Employment offers follow a formal interview process.
- Compensation is determined using experience, interview performance, role scope, internal equity, and expected impact.
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