2 дня назад
Senior Research Associate, Bioanalytical & Molecular Assays
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Senior Research Associate, Bioanalytical & Molecular Assays (Molecular Biology/Bioanalysis): Developing and validating molecular bioanalytical assays for RNA quantitation in biological matrices and clinical PK/PD analysis with an accent on qPCR, ddPCR, nucleic acid characterization, and GCLP-compliant workflows. Focus on transferring robust methods into clinical environments, reviewing analytical data, maintaining regulatory documentation, and improving laboratory processes through automation and Generative AI-enabled workflows.
Location: Cambridge, Massachusetts, United States, or Oxford, England. In-person 70/30 work model with 70% of work performed in the office.
Company
develops mRNA technologies, medicines, and clinical programs to transform healthcare.
What you will do
- Perform molecular and cellular bioanalytical assays, including gel electrophoresis, ddPCR, qPCR, and RT-qPCR, to quantify RNA in biological matrices.
- Develop, optimize, qualify, and validate phase-appropriate assays supporting clinical pharmacokinetic and pharmacodynamic analyses.
- Transfer bioanalytical methodologies into GCLP-compliant clinical workflows and review raw data, validation reports, and study reports for integrity and compliance.
- Collaborate with Clinical Operations, Sample Management, internal teams, and external laboratories to define sample journeys and laboratory manuals.
- Manage analytical equipment, critical reagents, SOPs, electronic laboratory notebooks, and supporting documentation.
- Improve laboratory efficiency and data interpretation through digital tools, automation, and Generative AI-enabled scientific workflows.
Requirements
- Master's degree with 5+ years of experience, or bachelor's degree with 8+ years of experience, in molecular biology or a related scientific discipline.
- Bioanalytical and GCLP/GLP experience performing clinical molecular assays.
- Hands-on experience with molecular biology and nucleic acid characterization techniques, including gel electrophoresis, capillary electrophoresis, and qPCR.
- Knowledge of GCLP requirements, analytical science regulations, and current industry expectations.
- Ability to communicate program objectives, analyze data, and present findings to team members and stakeholders.
Nice to have
- Experience with next-generation sequencing and genomics.
Culture & Benefits
- Collaborative, in-person work environment focused on scientific learning, innovation, teamwork, and mentorship.
- Competitive healthcare and voluntary benefit programs.
- Fitness, mindfulness, mental health, and family-building support, including fertility, adoption, and surrogacy benefits.
- Paid vacation, bank holidays, volunteer days, sabbatical, global recharge days, and discretionary year-end shutdown.
- Savings and investment programs plus location-specific benefits.
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