5 часов назад
Senior Associate Scientist (AI-Driven Drug Discovery)
84 000 - 105 000$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Senior Associate Scientist (AI-Driven Drug Discovery): Designing and synthesizing chemical compounds for drug discovery programs from hit identification through candidate selection with an accent on organic synthesis, catalysis, medicinal chemistry, and high-throughput experimentation. Focus on optimizing reaction conditions, analyzing biological and ADME-PK data, and applying machine learning insights to the design–make–test cycle.
Location: On-site at Therapeutics headquarters in San Diego, United States
Salary: $84,000–$105,000 for Sr Associate Scientist I; $96,000–$120,000 for Sr Associate Scientist II
Company
Therapeutics is a clinical-stage life-science and technology company developing medicines with an AI-driven drug discovery and development platform.
What you will do
- Design, synthesize, purify, and characterize chemical compounds at 10 mg–5 g scale using LCMS, HPLC, NMR, and automated parallel synthesis.
- Identify and optimize reaction conditions using screening kits and streamlined methodologies.
- Collaborate with the high-throughput experimentation team on parallel chemistry experiments.
- Analyze biological and ADME-PK data using cheminformatics tools and contribute to project strategy.
- Partner with computational chemists to apply machine learning insights to the design–make–test cycle and platform development.
- Present results, implications, and recommendations to project teams and senior leadership.
Requirements
- BS in Chemistry with 5+ years of pharmaceutical or biotechnology experience, or MS in Chemistry with 3+ years of pharmaceutical or biotechnology experience.
- Proven experience in multi-step organic synthesis, reaction optimization, SAR analysis, and scientific presentation.
- Hands-on experience with the drug discovery process and a demonstrated drug hunter mindset.
- Availability to work on-site in San Diego is required.
- Ability to work effectively in a fast-paced, highly collaborative research environment.
Nice to have
- Exposure to high-throughput experimentation.
- Familiarity with ADME-PK principles.
- 5+ years contributing to drug discovery projects.
- Experience with molecular modeling and structure-based drug design.
Culture & Benefits
- Cross-functional collaboration with medicinal chemists, biologists, DMPK scientists, computational chemists, machine learning researchers, and software engineers.
- Inclusive environment focused on diversity and collaboration.
- Company-paid healthcare and flexible spending accounts.
- Voluntary life insurance and 401(k) matching.
- Uncapped vacation.
- State-of-the-art San Diego facility with an on-site gym and dining.
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