Principal Investigator, Clinical Pharmacology & Pharmacometrics

Location: Wilmington, Delaware, United States

Company

hirify.global is a global biopharmaceutical company developing proprietary therapeutics in Hematology, Oncology, Inflammation and Autoimmunity, with operations in North America, Europe, and Asia.

What you will do

• Develop and execute pharmacometric modeling and simulation strategies for clinical development programs and regulatory submissions.
• Perform PK/PD and population PK/PD analyses and interpret results for clinical teams and management.
• Conduct semi-mechanistic PK/PD, PBPK, and QSP modeling and simulations for critical development decisions.
• Collaborate with clinical development, biostatistics, data management, medical writing, and regulatory affairs.
• Present findings internally and at external scientific meetings and publish manuscripts in peer-reviewed journals.

Requirements

• Ph.D. in Pharmacokinetics, Pharmacometrics, Pharmacology, Pharmaceutical Science, Chemical or Biomedical Engineering, Statistics, or a related field.
• 1–5 years of post-Ph.D. experience or 3–7 years of post-M.Sc. experience in population PK/PD, PBPK, and/or QSP modeling and simulations.
• Experience with multiple software packages such as R, NONMEM, Monolix, MATLAB, Simcyp, GastroPlus, or related pharmacokinetic and data visualization software.
• Scientific understanding of biopharmaceutical and ADME properties of small molecules and biologics.
• Experience scheduling and executing multiple programs and projects in a dynamic research environment.
• Excellent communication and presentation skills, with the ability to work independently.

Culture & Benefits

• Work in a science-driven biopharmaceutical research environment.
• Collaborate with multidisciplinary clinical development and regulatory functions.
• Contribute to research supporting therapeutics for patients with unmet medical needs.
• hirify.global is committed to creating a diverse and equal-opportunity work environment.