1 день назад
Senior Scientist, Cellular Genomics
93 600 - 156 000$
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Senior Scientist, Cellular Genomics (Single-Cell and Multi-Omics): Analyzing and integrating high-dimensional single-cell, spatial, and multi-omics datasets to generate mechanistic insights for inflammation and immunology drug development with an accent on reproducible computational workflows, biological interpretation, and targeted wet-lab genomics. Focus on connecting disease biology, perturbational responses, pharmacology, and translational data while ensuring assay quality and supporting mechanism-informed portfolio decisions.
Location: On premise in Cambridge, Massachusetts, United States. Relocation support may be available based on business needs and eligibility.
Annual base salary: $93,600–$156,000, plus a 12.5% bonus target and eligibility for a share-based long-term incentive program.
Company
is a global pharmaceutical and biotechnology company developing medicines through research and drug-development programs.
What you will do
- Lead computational analysis of single-cell, spatial, transcriptomic, epigenomic, and multi-omics datasets.
- Perform quality assessment, preprocessing, statistical analysis, visualization, biological annotation, and reproducible interpretation.
- Translate genomic data into mechanistic hypotheses, biomarker concepts, pharmacology interpretations, and decision-relevant insights.
- Integrate cellular genomics with disease biology, perturbation biology, pharmacology, translational datasets, and project hypotheses.
- Provide wet-lab genomics input on study design, sample processing, assay selection, data-quality requirements, and workflow interpretation.
- Support limited hands-on wet-lab execution and troubleshooting for single-cell, sequencing, and spatial workflows.
Requirements
- BS with 6+ years, MS with 4+ years, or PhD with 0–3+ years of relevant experience in computational biology, genomics, systems biology, immunology, bioinformatics, or a related field.
- Practical experience analyzing high-dimensional genomic datasets using reproducible computational workflows.
- Proficiency in R, Python, statistics, data visualization, quality control, standard bioinformatics pipelines, and multi-omics interpretation.
- Hands-on experience with wet-lab genomic assay workflows, including sample processing, sequencing, single-cell, or spatial profiling methods.
- Permanent authorization to work in the United States is required; U.S. work visa sponsorship is not available now or in the future.
Nice to have
- Experience analyzing single-cell, spatial, sequencing, or multi-omics datasets in inflammation, immunology, neuroinflammation, or autoimmunity.
- Experience with version-controlled workflows, command-line tools, scalable data processing, statistical modeling, visualization, and reproducible reporting.
- Experience with machine learning, computational, statistical, or approved agentic tools for high-dimensional data analysis.
- Experience integrating genomic data with perturbational biology, pharmacology, translational datasets, or disease models.
- Experience with biomarkers, translational medicine, or mechanism-informed drug-development decisions.
Culture & Benefits
- Full-time employment with comprehensive medical, prescription drug, dental, and vision coverage.
- 401(k) plan with matching contributions and an additional retirement savings contribution.
- Paid vacation, holidays, personal days, caregiver and parental leave, and medical leave.
- Participation in the Global Performance Plan and eligibility for a share-based long-term incentive program.
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