3 дня назад
Senior Scientist, Target Discovery & Biology (Functional Genomics)
Мэтч & Сопровод
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Описание вакансии
Текст:
TL;DR
Senior Scientist, Target Discovery & Biology (Functional Genomics): Advancing target discovery and validation across therapeutic areas by applying functional genomics in disease-relevant systems from in vitro to in vivo models with an accent on molecular biology, cell engineering, and genetic screening. Focus on leading projects from target identification through mechanism-of-action studies, integrating genetic and multi-omics insights, and solving complex biological questions through large-scale CRISPR-based screens.
Location: South San Francisco, California, United States; corporate headquarters in Thousand Oaks, California.
Company
is a biotechnology company developing medicines across oncology, inflammation, general medicine, and rare disease.
What you will do
- Apply functional genomics approaches across therapeutic areas to discover novel targets and address key biological questions.
- Lead, support, and execute projects from inception through target identification, validation, and mechanism-of-action studies.
- Use disease-relevant biological models ranging from in vitro to in vivo systems.
- Contribute to a collaborative, creative, and scientifically rigorous research culture.
Requirements
- PhD, PharmD, or MD with relevant postdoctoral scientific experience in Target Discovery and Biology; alternatively, a master’s degree with 3 years or a bachelor’s degree with 5 years of relevant experience.
- Strong experience in molecular biology and cell engineering.
- Experience executing large-scale, complex, or in vivo genetic screens, particularly CRISPR-based screens, and follow-up validation studies.
- Familiarity with data-driven discovery approaches and integration of genetic or multi-omics insights.
- Strong organizational and communication skills for cross-site collaboration in a matrixed research environment.
- Demonstrated scientific productivity, innovation, and successful work in new research areas.
Nice to have
- Experience with complex and co-culture in vitro models.
- Additional experience applying functional genomics to target discovery across diverse indications.
Culture & Benefits
- Collaborative, innovative, and science-based work environment.
- Comprehensive medical, dental, vision, life, disability, and flexible spending benefits.
- Retirement and savings plan with company contributions.
- Annual bonus program and stock-based long-term incentives.
- Paid time-off plans and career development opportunities.
- Flexible work models where applicable.
Hiring process
- Applications are accepted until a sufficient number of applications is received or a candidate is selected.
- Visa sponsorship is not guaranteed.
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