9 часов назад
Vice President, Neuroscience
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Vice President, Neuroscience (Neurodegenerative Diseases): Leading the neuroscience portfolio from exploratory target selection through clinical development with an accent on preclinical pharmacology, translational biomarkers, and PROTAC degrader programs. Focus on building multidisciplinary teams, establishing PK/PD relationships, developing disease-relevant in vivo models, and advancing regulatory and clinical strategies for severe neurologic disorders.
Location: New Haven, Connecticut, United States; hybrid work with attendance at the main office 3+ days per week
Company
is a biotechnology company developing therapies that degrade disease-causing proteins through its PROTAC Discovery Engine platform, with programs in oncology and neurodegenerative diseases.
What you will do
- Lead the neuroscience organization and advance high-impact programs from discovery through clinical development.
- Direct exploratory target selection, target validation, lead identification, and compound optimization using in vitro and in vivo pharmacology.
- Oversee PK/PD studies, target engagement, pathway biology, translational biomarker assays, and human dose projections.
- Build, mentor, and inspire a multidisciplinary neuroscience team focused on preclinical pharmacology and translational medicine.
- Collaborate with Research, Translational Sciences, Clinical Development, Regulatory, and Biometrics leaders on integrated portfolio strategies.
- Lead collaborations with biopharma partners, academic institutions, CROs, scientific investigators, and patient advocacy groups.
Requirements
- Ph.D. with 15+ years of industry or biotechnology leadership experience in neurobiology and pharmacology.
- Established scientific reputation in neuroscience and neurodegenerative disease research, demonstrated through publications, scientific leadership, and collaborations.
- Extensive experience with disease-relevant in vivo models, quantitative and statistical analysis, translational biomarker endpoints, and clinical candidate development.
- Experience authoring or contributing to IND and CTA documents, clinical protocols, regulatory submissions, and study reports.
- Proven ability to build and lead multidisciplinary teams and cultivate collaborations across academic, clinical, industry, and research organizations.
- Must be authorized to work in the United States without current or future employer-sponsored visa sponsorship.
Culture & Benefits
- Hybrid environment combining office, laboratory, and remote work, with regular on-site engagement.
- Culture centered on innovation, collaboration, accountability, trust, and scientific excellence.
- Medical, vision, and dental coverage.
- Group and supplemental life insurance and additional employee benefits.
- Base and incentive compensation package designed to support employee and family health, wellness, and financial security.
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