Scientist I, Biologics Outsourcing Specialist (Biologics)

Location: North Chicago, Illinois, United States; onsite position

Salary: $75,000–$142,500 per year

Company

hirify.global discovers and delivers medicines and solutions for serious health issues across areas including immunology, oncology, neuroscience, and aesthetics.

What you will do

• Coordinate and manage outsourced therapeutic biologics production at CROs, covering requests from 100 mg to 50 grams.
• Manage protein production activities including sequence design, expression method, scale selection, primary capture, secondary purification, and quality control.
• Plan outsourcing projects, design strategies, manage risks, and track project status with requestors and collaborators.
• Develop vendor data-sharing workflows and support accurate transfer of project data into LIMS.
• Perform biophysical characterization and analytical QC, including SEC, intact and reduced mass spectrometry, endotoxin, and HCP testing.
• Resolve scientific problems, communicate unexpected findings, and analyze and report experimental data.

Requirements

• Onsite work in North Chicago, Illinois, United States is required.
• Bachelor's or master's degree in biology, chemistry, biochemistry, or a related field, with typically 5+ years of experience for a bachelor's degree or 2+ years for a master's degree.
• Experience with biologics production, including plasmid design, stable and transient CHO cell expression, Protein A, CH1, kappa select, AEX, CEX, and HIC purification.
• Experience working with CROs on protein production projects.
• Experience with analytical QC of biologics, including SEC, intact and reduced mass spectrometry, endotoxin and HCP testing, peptide mapping, released glycan analysis, and CE-SDS.
• Experience in process development and optimization, including expression optimization and purification process development.

Culture & Benefits

• Work supports worldwide drug discovery efforts and the development of therapeutic biologics.
• Benefits include paid vacation, holidays, sick leave, medical, dental, and vision insurance, and a 401(k) for eligible employees.
• Eligibility to participate in short-term incentive programs.
• Collaboration with internal colleagues, external partners, and CRO vendors.