2 часа назад
Research Associate II/Senior Research Associate, Analytical Development (Gene Editing)
Мэтч & Сопровод
Для мэтча с этой вакансией нужен Plus
Описание вакансии
Текст:
TL;DR
Research Associate II/Senior Research Associate, Analytical Development (Gene Editing): Developing and qualifying analytical assays to characterize transgene expression and function in genetically modified porcine cells with an accent on cell culture, flow cytometry, ELISA, and PCR. Focus on troubleshooting assay failures, optimizing laboratory workflows, managing critical reagents, and transferring methods to QC.
Location: Cambridge, Massachusetts, United States; Workplace: On-site
Company
develops gene editing and xenotransplantation products using molecular and cellular engineering technologies.
What you will do
- Develop, optimize, troubleshoot, and execute analytical assays for genetically edited porcine cells and animals.
- Perform cell culture, including isolation, growth, and maintenance of primary endothelial cells from porcine organs.
- Characterize cells and transgene expression using flow cytometry, ELISA, conventional PCR, real-time PCR, and potency assays.
- Identify assay anomalies, conduct root-cause analyses, and propose corrective paths.
- Manage reagent inventories, batch samples, and execute full-plate assays to optimize laboratory resources.
- Partner with QC on analytical method transfers and communicate scientific findings at group and company meetings.
Requirements
- Bachelor of Science degree and at least 4 years of industry experience in cell biology, immunology, biomedical engineering, or a related discipline.
- Experience developing, troubleshooting, and executing assays for transgene expression and potency.
- Proficiency with mammalian primary cell and cell-line culture, including aseptic techniques.
- Expertise in ELISA, flow cytometry/FACS, PCR, and cellular and molecular biology techniques.
- Ability to independently prioritize work across multiple concurrent projects and adapt in a fast-paced environment.
- Strong interpersonal and teamwork skills, with demonstrated laboratory efficiency and inventory-management experience.
Culture & Benefits
- Full-time, lab-based role within a small Analytical Development team.
- Collaborative, proactive, and coachable working environment.
- Opportunity to contribute to multiple research projects in a fast-paced startup environment.
- Focus on building a productive laboratory environment and supporting cross-functional alignment.
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