Executive Director, Early Clinical Development, NHL Program Lead

Location: Hybrid role based in Somerset, New Jersey, United States. Applicants must be authorized to work in the United States; employment eligibility is verified through E-Verify. Travel up to 15–20% may be required.

Base pay: $338,656–$444,486 per year, plus performance-based bonus and/or equity for eligible employees.

Company

hirify.global is a biotechnology company developing cell therapies, including CAR-T, TCR-T, NK cell-based, and in vivo cell therapy approaches for serious diseases.

What you will do

• Lead the Non-Hodgkin Lymphoma clinical development program across early-stage and, when appropriate, later-stage development.
• Develop and execute integrated strategies covering indication selection, patient populations, endpoints, dose selection, biomarkers, safety monitoring, and evidence generation.
• Lead the design, execution, monitoring, interpretation, and reporting of first-in-human, dose-escalation, dose-expansion, proof-of-concept, and other early clinical studies.
• Provide clinical leadership for protocols, clinical study reports, investigator brochures, regulatory documents, IND submissions, publications, and presentations.
• Oversee medical monitoring, eligibility and safety reviews, dose-escalation decisions, emerging data interpretation, and benefit-risk assessment.
• Supervise NHL clinical development medical directors and clinical scientists while partnering with translational science, regulatory, safety, biostatistics, operations, CMC, project management, and commercial functions.

Requirements

• MD, MD-PhD, or equivalent medical degree, with board certification in hematology or oncology.
• At least 6 years of clinical development experience in biopharmaceutical industry and/or academic medicine, including substantial experience with hematologic malignancies.
• Experience designing and leading early clinical development programs, including first-in-human studies, dose escalation and expansion, dose selection, safety monitoring, clinical data review, and proof-of-concept generation.
• Strong understanding of hematology/oncology trial design, response assessment, safety monitoring, dose optimization, biomarkers, and benefit-risk evaluation.
• Experience with clinical and regulatory documents, IND submissions, health authority interactions, and cross-functional development teams.
• Excellent communication, collaboration, influencing, negotiation, conflict-management, and decision-making skills.

Nice to have

• Experience in Non-Hodgkin Lymphoma.
• Experience with cell therapy, CAR-T, in vivo cell therapy, T-cell engagers, bispecific antibodies, or other immuno-oncology modalities.
• Experience contributing to pivotal development strategy and registration-enabling planning.

Culture & Benefits

• Medical, dental, and vision insurance with a 401(k) plan and company match vesting fully on day one.
• Eight weeks of paid parental leave after three months of employment.
• Paid vacation, personal and sick time, floating holidays, and eleven company holidays.
• Flexible spending and health savings accounts, disability coverage, life insurance, legal assistance, commuter benefits, and family care resources.
• Benefits are available exclusively to permanent full-time employees; contractors are not eligible.