Senior Computational Biologist (Precision Oncology)

Location: Hybrid, based in the Salt Lake City, Utah or New York, New York office; at least 50% office attendance required

Annual base salary: $166,980–$220,660 in New York City or $151,800–$200,600 in Salt Lake City, plus annual bonus and equity compensation.

Company

hirify.global is a clinical-stage TechBio company using the AI-native hirify.global OS and multimodal biological data to accelerate drug discovery and development.

What you will do

• Evaluate molecular evidence to nominate and validate targets in precision oncology.
• Pilot computational methods for target discovery, validation, and early patient population hypotheses.
• Define criteria for target data packages and early patient population strategies.
• Integrate analysis methods with platform and engineering teams to scale discovery capabilities.
• Collaborate with biologists, medicinal chemists, translational experts, portfolio leads, and data specialists to build decision-ready data packages.
• Present analyses to stakeholders and decision makers to support program milestones and investment decisions.

Requirements

• PhD in computational biology, bioinformatics, systems biology, cancer biology, or a related field with a strong computational focus and 3+ years of biotech or pharma experience; or an MS with 5+ years of relevant industry experience.
• Experience solving fundamental problems in early drug discovery.
• Domain expertise in precision oncology and target identification.
• Strong understanding of patient genetics and the druggability of disease-relevant pathways.
• Experience applying probabilistic, statistical, or machine learning methods to complex biological or clinical data using Python or R.
• Exceptional data visualization and cross-functional scientific communication skills.

Nice to have

• Experience building target discovery engines using public and proprietary datasets.
• Experience designing high-throughput CRISPR or small-molecule perturbation screens.
• Exposure to advancing drug programs from proof of concept to IND.

Culture & Benefits

• Collaborative work across computational science, biology, chemistry, engineering, and translational functions.
• Career development and technical feedback within a diverse computational drug discovery group.
• Annual bonus, equity compensation, and a comprehensive benefits package.
• Values centered on scientific integrity, experimentation, urgency, ownership, and cross-functional collaboration.