Scientist II, Radiochemistry (Preclinical)

TL;DR

Scientist II, Radiochemistry (Preclinical): Designing and executing the synthesis, purification, and formulation of radiotracers for in vivo imaging and efficacy studies with an accent on PET/SPECT radiopharmaceuticals and analytical method validation. Focus on optimizing radio labeled compounds for complex biological markers and managing multiple preclinical nuclear medicine projects.

Location: Must be based in Needham, MA

Salary: $65,305–$121,282

Company

A company specializing in radiochemistry and preclinical nuclear medicine research for external sponsors.

What you will do

• Manage the production of radiotracers used in PET/SPECT imaging and therapeutic research studies.
• Design, develop, and optimize radio labeled compounds targeting complex biological markers.
• Create and validate purification methods for small and large molecules and analytical methods for HPLC and TLC.
• Operate and maintain analytical and automated radiochemistry synthesis units.
• Analyze data, recognize aberrant results, and propose corrective actions.
• Mentor junior team members and provide scientific expertise in communication with Sponsors.

Requirements

• Ph.D. in Chemistry or relevant field with 3+ years of experience, or M.S. with 5+ years of experience in an academic or pharmaceutical lab.
• Experience working with radioactive materials in a safe and compliant manner.
• Working knowledge and experience with HPLC and TLC techniques in radiochemistry.
• Ability to lift more than 40 pounds.
• English: Fluent (C1) required.

Nice to have

• Experience in conjugation with chelators and labeling with radiometals.
• Prior experience with F-18 radiochemistry and radioiodination methods.

Culture & Benefits

• Comprehensive medical, dental, and vision benefits for employees and their families, including FSA.
• 401(k) program, life, accident, and disability insurance.
• Paid time off policy including holidays and sick time.
• Access to internal growth and development programs and professional trainings.