Senior Principal AI Engineer (Agentic AI Platform)

TL;DR

Senior Principal AI Engineer (Agentic AI Platform): Designing and building shared platform services for agentic AI workflows with an accent on orchestration, observability, and model integration. Focus on enabling a build/bring-your-own-agents capability to accelerate AI adoption across the enterprise.

Location: Must be based in or able to work from Boston, MA (Hybrid)

Salary: $188,000–$282,000

Company

Vertex is a global biotechnology company that invests in scientific innovation.

What you will do

• Architect and develop shared AI/agentic platform services for enterprise products.
• Design a build/bring-your-own-agents capability for internal teams.
• Establish reusable frameworks, SDKs, and guardrails for custom agent development.
• Define agent lifecycle management including registration, deployment, and monitoring.
• Build robust integrations with foundation models, APIs, and enterprise tools.
• Optimize platform performance, scalability, and cost efficiency for production AI systems.

Requirements

• Must be based in or able to work from Boston, MA.
• Significant industry experience in AI platform development at a senior or principal level.
• Proven track record of delivering production-scale AI or ML platforms.
• Strong experience with distributed systems, microservices, and cloud-native applications.
• Deep understanding of AI-native software engineering and responsible AI practices.
• Ability to lead complex technical initiatives across cross-functional teams.

Nice to have

• Advanced degree in Computer Science, AI, or Machine Learning.
• Experience in regulated industries such as biotechnology or pharmaceuticals.
• Knowledge of vector databases and retrieval-augmented generation (RAG).
• Experience implementing AI governance and compliance-oriented technical solutions.

Culture & Benefits

• Comprehensive medical, dental, and vision benefits.
• Generous paid time off including summer and winter company shutdowns.
• Educational assistance programs and student loan repayment.
• 401(k) retirement plan with company matching.
• Flexible work environment with hybrid policy.