Senior Scientist I (Drug Discovery)

TL;DR

Senior Scientist I (Drug Discovery): Responsible for advanced metabolite identification and elucidation within the metabolism-biotransformation function with an accent on liquid chromatography and mass spectrometry. Focus on designing complex in vivo and in vitro metabolism studies, interpreting high-resolution data, and ensuring regulatory compliance for IND and NDA applications.

Location: On-site in Cranbury, NJ, USA

Salary: $100,000 – $115,000

Company

hirify.global is a global pharmaceutical and biopharmaceutical outsourcing company providing comprehensive R&D and manufacturing services.

What you will do

• Perform drug metabolite identification using liquid chromatography-tandem high-resolution accurate mass spectrometry, NMR, and other analytical methods.
• Elucidate metabolic pathways in biological matrices (blood, plasma, excreta) using HPLC with radioactivity detection and LC-MS/MS.
• Design and conduct complex in vivo and in vitro metabolism studies, providing multiple strategic approaches during planning.
• Act as a study director or project manager, overseeing the planning, conduct, and timely delivery of high-quality projects.
• Mentor and train other scientists on technical and personal development while reviewing calculations, records, and reports.
• Author comprehensive reports and participate in the creation of Standard Operating Procedures (SOPs).

Requirements

• PhD with 3+ years, Master's with 10+ years, or Bachelor's with 13+ years of related experience.
• Degree in Chemistry, Biology, or a related science field.
• Strong expertise in LC-MS/MS, NMR, and interpretation of complex mass spectrometry data.
• Deep knowledge of ADME, PK, and metabolism.
• Familiarity with regulatory guidance, specifically MIST guidance and acceptance criteria for discovery, IND, and NDA stages.
• Must be able to work on-site in Cranbury, NJ.

Nice to have

• Emerging skills in novel experimental methods, concepts, and techniques.

Culture & Benefits

• Structured professional environment with a focus on high-quality data and timely delivery.
• Opportunities for leadership through mentoring and coaching junior staff.
• Commitment to safety and a well-organized research environment with adherence to non-GLP guidelines.
• Equal opportunity employer ensuring a diverse and inclusive workplace.