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2 months ago

Immunology Senior Research Scientist (Spatial Transcriptomics)

124 200 - 186 400$
Work format
onsite
Work type
fulltime
Grade
senior
English
b2
Country
US
This vacancy is from Hirify.Global listVacancy from Hirify Global, list of international tech companies
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Job description

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TL;DR
Immunology Senior Research Scientist (Spatial Transcriptomics): Leading the design and execution of spatial transcriptomics studies to drive mechanistic insights into disease biology and therapeutic response. Focus on integrating multi-modal datasets, optimizing tissue-based molecular profiling workflows, and collaborating across cross-functional teams to advance drug discovery and biomarker strategies.

Location: On-site in Seattle, WA (5 days per week)

Salary: $124,200 - $186,400

Company

hirify.global is a global biotechnology company dedicated to creating transformative medicines for people with serious diseases.

What you will do

  • Design and execute spatial transcriptomics studies to address key biological questions in disease-relevant tissues.
  • Characterize tissue architecture, cellular microenvironments, and cell-cell interactions.
  • Integrate spatial transcriptomics data with single-cell RNA-seq, proteomics, and imaging datasets.
  • Develop and validate robust workflows for sample preparation, assay execution, and quality control.
  • Partner with cross-functional teams in disease biology, pharmacology, and bioinformatics to inform program strategy.
  • Mentor junior scientists and contribute to establishing best practices for spatial biology.

Requirements

  • PhD in Immunology, Cell Biology, Molecular Biology, or related discipline with 2+ years of experience (or equivalent Master's/Bachelor's degree with relevant experience).
  • Deep expertise in spatial transcriptomics and tissue-based molecular profiling.
  • Proficiency in R and/or Python for spatial data analysis and visualization.
  • Experience with fresh frozen and FFPE tissue processing and assay optimization.
  • Strong understanding of transcriptomics, RNA biology, and cellular heterogeneity.
  • Must be able to work on-site in Seattle, WA, five days per week.

Nice to have

  • Hands-on experience with platforms like 10x Genomics Visium or Nanostring CosMx.
  • Experience with histology, immunofluorescence, and multiplexed tissue profiling.
  • Background in drug discovery, translational research, or clinical biomarker development.
  • Knowledge of spatial proteomics or broader tissue-based profiling approaches.

Culture & Benefits

  • Comprehensive medical, dental, and vision benefits.
  • Generous paid time off, including company-wide summer and winter shutdowns.
  • Educational assistance programs, including student loan repayment.
  • 401(k) matching and charitable donation matching.
  • Supportive environment focused on professional growth and scientific innovation.

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