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2 дня назад

Scientist, Immunology

120 000 - 175 000$
Формат работы
onsite
Тип работы
fulltime
Грейд
senior
Английский
b2
Страна
US
Вакансия из списка Hirify.GlobalВакансия из Hirify Global, списка международных tech-компаний
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Описание вакансии

Текст:
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TL;DR
Scientist, Immunology (Cell Assays/Drug Discovery): Designing and optimizing cell-based assays to evaluate small-molecule mechanisms of action and support hit-to-lead and lead optimization with an accent on immune signaling, primary cell techniques, and cellular profiling. Focus on developing medium- to high-throughput assays, generating dose-response and IC50 data, troubleshooting complex experiments, and guiding multidisciplinary drug discovery decisions.

Location: Full-time onsite in Monrovia, California, United States

Salary: $120,000–$175,000 annually, depending on experience

Company

hirify.global is a venture-backed biotechnology company combining nanotechnology, experimental science, machine learning, automation, and proprietary chemical data to discover and develop small-molecule therapeutics.

What you will do

  • Design experiments to confirm the mechanisms of action of small-molecule hits from binding and virtual screens.
  • Develop, optimize, and run cell-based assays to profile on-target and off-target activity.
  • Adapt assays for medium- to high-throughput screening, dose-response analysis, and IC50 generation.
  • Review literature and interpret experimental data to support internal immunology targets and therapeutic programs.
  • Manage CROs for reagent development and in vitro testing when needed.
  • Collaborate with chemists, computational scientists, and other multidisciplinary teams to guide project decisions.

Requirements

  • PhD in immunology, molecular biology, cell biology, or a related field with 3+ years of small-molecule drug discovery experience, or an MSc with 10+ years of industry experience.
  • Strong background in immunology and immune signaling pathways.
  • Extensive hands-on experience with cell culture, cell-based assays, reporter assays, gene and protein expression, and intracellular techniques.
  • Proficiency in primary cell isolation, differentiation, culture, and flow cytometry.
  • Experience establishing robust small-molecule dose-response assays and generating IC50 data.
  • Strong troubleshooting, organizational, interpersonal, communication, and collaborative research skills.

Culture & Benefits

  • Hands-on, collaborative, and fast-paced research environment.
  • Work alongside experts in artificial intelligence, chemistry, drug discovery, automation, and nanotechnology.
  • Company stock option plan.
  • 3% retirement safe harbor contribution.
  • Fully paid health, dental, and vision insurance for employees and eligible family members, plus life and disability coverage.

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