Scientist (Biotech)

TL;DR

Scientist (Biotech): Researching and developing next-generation in-vivo CAR-T cell therapies with an accent on immune cell-based analytics, viral vector characterization, and solid tumor model evaluation. Focus on designing and optimizing research projects to advance the discovery pipeline for cancer and autoimmune disease indications.

Location: Must be based in Philadelphia, PA (Hybrid role)

Salary: $127,313 - $167,099 USD

Company

hirify.global is a global biotechnology company dedicated to developing advanced cell therapies, including CAR-T and NK cell-based immunotherapies, to treat life-threatening diseases.

What you will do

• Lead, design, and optimize research focused on next-generation in-vivo CAR-T therapies.
• Isolate immune cells and execute evaluations using in-vitro assays and in-vivo mouse models.
• Perform cell biology techniques including cell culture, transfection, FACS, and functional assays.
• Package and titer engineered viruses, characterizing particles with protein and PCR-based assays.
• Manage and evaluate critical research data using electronic lab notebooks (ELN).
• Present research results to internal groups and forums to meet project timelines.

Requirements

• Recent PhD graduate in Immunology or related life sciences discipline (within the last 5 years).
• 3-4 years of experience in cell and gene therapy required.
• Extensive experience in immune cell-based analytics, including multi-parameter flow-cytometry and ELISA/MSD multiplex assays.
• Experience with lentivirus particle characterization and quantification using molecular and flow-based assays.
• Deep knowledge of immunology, immunotherapy, and solid tumor models.
• Proficiency in advanced gene delivery methods using LVV, VLP, or LNP technologies.

Nice to have

• Experience with solid tumor models and in-vivo cell-specific gene delivery.
• Prior experience with in-vivo CAR-T research.

Culture & Benefits

• Comprehensive medical, dental, and vision insurance.
• 401(k) retirement plan with company match vesting on day one.
• Eight weeks of paid parental leave after three months of employment.
• Generous paid time off policy including vacation, personal, sick time, and eleven company holidays.
• Access to well-being initiatives, family planning resources, and peer-to-peer recognition programs.